DNA bundle formation induced by cationic surfactants

被引：31

作者：

McLoughlin, D ^{[1
]}

Delsanti, M

Tribet, C

Langevin, D

机构：

[1] Univ Paris 11, Phys Solides Lab, Orsay, France

[2] ESPCI, Lab Physicochim Macromol, Paris, France

[3] ICI PLC, Wilton Ctr, Strat Technol Grp, Redcar TS10 4RF, England

来源：

EUROPHYSICS LETTERS | 2005年 / 69卷 / 03期

关键词：

D O I：

10.1209/epl/i2004-10367-2

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We have evidenced bundle formation in DNA solutions, induced by the addition of a monovalent cationic surfactant to a solution of short DNA rods. The bundles are rodlike, with a large axial ratio (similar to 10). Their formation is very likely controlled not; only by electrostatic interactions, but also by hydrophobic interactions between surfactant chains, once bound to the DNA. The bundles have diameters and lengths both remarkably well defined and possess internal organisation. The value of the diameter is close to that predicted by a model in which interactions are mediated by condensed counterions; the length might be limited by steric hindrance due to bundle overlapping or by intrinsic chain flexibility.

引用

页码：461 / 467

页数：7

共 30 条

[1] DNA CONDENSATION BY COBALT HEXAAMMINE(III) IN ALCOHOL-WATER MIXTURES - DIELECTRIC-CONSTANT AND OTHER SOLVENT EFFECTS [J].