Development and Assessment of a Modified Pediatric Crohn Disease Activity Index

被引：25

作者：

Leach, Steven T. ^{[2
]}

Nahidi, Lily ^{[2
]}

Tilakaratne, Samantha ^{[1
]}

Day, Andrew S. ^{[2
]}

Lemberg, Daniel A. ^{[1
]}

机构：

[1] Sydney Childrens Hosp, Dept Gastroenterol, Sydney, NSW, Australia

[2] Univ New S Wales, Sch Womens & Childrens Hlth, Sydney, NSW 2052, Australia

来源：

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION | 2010年 / 51卷 / 02期

关键词：

Crohn disease; fecal calprotectin; modified PCDAI; INFLAMMATORY-BOWEL-DISEASE; INTESTINAL INFLAMMATION; FECAL CALPROTECTIN; CHILDREN; MARKER;

D O I：

10.1097/MPG.0b013e3181d13609

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The Pediatric Crohn Disease Activity Index (PCDAI) is an established and validated measure of disease activity in children with Crohn disease. However, its use in the research setting can be limited because of ambiguity of the subjective and anthropometric components of the index. Here we propose and evaluate a modified PCDAI (Mod PCDAI) consisting of the laboratory measures of the PCDAI plus C-reactive protein. This Mod PCDAI can provide an indication of disease activity because it correlates with the PCDAI, physicians' global assessment, and fecal calprotectin, and therefore may provide a suitable alternative to the PCDAI when required.

引用

页码：232 / 236

页数：5

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