An efficient new procedure for the one-pot conversion of aldehydes into the corresponding nitriles

被引：45
作者：
Zhu, Jia-Liang [1 ]
Lee, Fa-Yen
Wu, Jen-Dar
Kuo, Chun-Wei
Shia, Kak-Shan
机构：
[1] Natl Hlth Res Inst, Div Biotechnol & Pharmaceut Res, Miaoli 350, Taiwan
[2] Natl Dong Hwa Univ, Dept Chem, Hualien 974, Taiwan
来源：
SYNLETT | 2007年 / 08期
关键词：
aldehydes; nitrites; ethyl dichlorophosphate; DBU; dehydration;
D O I：
10.1055/s-2007-980338
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new and efficient procedure for the one-pot conversion of various aldehydes into the corresponding nitrites under mild reaction conditions has been developed. The ethyl dichlorophosphate/ DBU-mediated dehydration of aldoxime intermediates was utilized as a key operation to effect the transformation.
引用
收藏
页码：1317 / 1319
页数：3
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