Dual Blades: The Role of Musashi 1 in Zika Replication and Microcephaly

被引：3
作者：
Klein, Robyn S. [1 ,2 ,3 ]
机构：
[1] Washington Univ, Sch Med, Dept Internal Med, St Louis, MO 63110 USA
[2] Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA
[3] Washington Univ, Sch Med, Dept Neurosci, St Louis, MO 63110 USA
来源：
CELL HOST & MICROBE | 2017年 / 22卷 / 01期
关键词：
VIRUS;
D O I：
10.1016/j.chom.2017.06.015
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Infection with Zika virus (ZIKV) during pregnancy may cause severe developmental defects in the human brain via unknown mechanisms. In a recent issue of Science, Chavali et al. (2017) identified a neural progenitor cell (NPC)-specific RNA binding protein that may underlie the high levels of ZIKV replication and apoptosis observed in these cells during congenital infections.
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页码：9 / 11
页数：4
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