Lithium prophylaxis in early-onset Bipolar disorder: a descriptive study

被引：3

作者：

Selvarajan, Sandhiya ^{[1
]}

Manohar, Harshini ^{[2
]}

Das, Saibal ^{[1
]}

Sakkarabani, Priyanka ^{[2
]}

Kandasamy, Preeti ^{[2
]}

机构：

[1] JIPMER, Dept Clin Pharmacol, Dhanvantri Nagar 605006, Puducherry, India

[2] JIPMER, Dept Psychiat, Dhanvantri Nagar 605006, Puducherry, India

来源：

ASIAN JOURNAL OF PSYCHIATRY | 2019年 / 44卷

关键词：

Bipolar; Early-onset; Adolescent; Treatment; Lithium;

D O I：

10.1016/j.ajp.2019.07.053

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Subjects fulfilling DSM 5 criteria of Bipolar I disorder with onset before 18 years on Lithium prophylaxis were included. A total of 575 subjects with Bipolar Disorder were screened, 141 had early-onset Bipolar disorder, 72 patients were on Lithium and 52 provided informed consent and entered the study. Thirty-four were in the prospective group, and 18 were in the retrospective arm. Mean age at onset was 16.13 (1.40) years. About 31% (n = 16) were initiated on Lithium following first episode. Mean age at initiating lithium was 19.73 (3.82) years. Clinical profile and treatment response of early-onset bipolar disorder in the Indian context needs further study.

引用

页码：172 / 174

页数：3

共 14 条

[1]

[Anonymous], 2017, SCI PRACT LITHIUM TH

[2]

Ayano G., 2016, Austin J Psychiatry Behav Sci, V3, P1053

[3] Lithium Treatment in Children and Adolescents [J].

Duffy, Anne ;

Grof, Paul .

PHARMACOPSYCHIATRY, 2018, 51 (05) :189-193

[4] Efficacy of pharmacotherapy in bipolar disorder: a report by the WPA section on pharmacopsychiatry [J].

Fountoulakis, Konstantinos N. ;

Kasper, Siegfried ;

Andreassen, Ole ;

Blier, Pierre ;

Okasha, Ahmed ;

Severus, Emanuel ;

Versiani, Marcio ;

Tandon, Rajiv ;

Moeller, Hans-Juergen ;

Vieta, Eduard .

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, 2012, 262 :S1-S48

[5] Child bipolar I disorder - Prospective continuity with adult bipolar I disorder; Characteristics of second and third episodes; Predictors of 8-year outcome [J].

Geller, Barbara ;

Tillman, Rebecca ;

Bolhofner, Kristine ;

Zimerman, Betsy .

ARCHIVES OF GENERAL PSYCHIATRY, 2008, 65 (10) :1125-1133

[6]

Jairam R, 2008, Minerva Pediatr, V60, P59

[7]

Kandasamy P., 2016, CHILD ADOLESCENT PSY, V1, P51

[8] Clinical factors associated with lithium treatment response in bipolar disorder patients from India [J].

Kapur, Vaisnvy ;

Nadella, Ravi Kumar ;

Raghuraman, Bharathram Sathur ;

Saraf, Gayatri ;

Mishra, Shree ;

Srinivasmurthy, Nithyananda ;

Jain, Sanjeev ;

Del Zompo, Maria ;

Viswanath, Biju .

ASIAN JOURNAL OF PSYCHIATRY, 2019, 39 :165-168

[9] Starting lithium prophylaxis early v. late in bipolar disorder [J].

Kessing, Lars Vedel ;

Vradi, Eleni ;

Andersen, Per Kragh .

BRITISH JOURNAL OF PSYCHIATRY, 2014, 205 (03) :214-220

[10]

Merikangas K. R., 2011, Textbook in psychiatric epidemiology, P329

← 1 2 →