A facile method for catalyst immobilisation on silica: nickel-catalysed Kumada reactions in mini-continuous flow and batch reactors

被引：69
作者：
Phan, NTS
Brown, DH
Styring, P
机构：
[1] Univ Sheffield, Dept Chem & Proc Engn, Sheffield S1 3JD, S Yorkshire, England
[2] Univ Western Australia, Sch Biomed & Chem Sci, Crawley 6009, Australia
来源：
GREEN CHEMISTRY | 2004年 / 6卷 / 10期
关键词：
D O I：
10.1039/b405203j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An unsymmetrical salen-type nickel(II) complex was readily immobilised onto functionalised silica using a convenient tethering method. The supported complex was an effective recyclable heterogeneous catalyst in a room temperature cross-coupling reaction between 4-bromoanisole and phenylmagnesium chloride. Leaching of the metal into solution from the supported catalyst proved almost negligible. The silica-supported catalyst was ideal for use in a mini-continuous flow reactor since it did not exhibit swelling which is common and a problem for organic polymer resin supports.
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收藏
页码：526 / 532
页数：7
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