Prevalence and Predictors of Per- and Polyfluoroalkyl Substances (PFAS) Serum Levels among Members of a Suburban US Volunteer Fire Department

被引:30
|
作者
Graber, Judith M. [1 ]
Black, Taylor M. [2 ]
Shah, Nimit N. [1 ]
Caban-Martinez, Alberto J. [3 ]
Lu, Shou-en [1 ]
Brancard, Troy [1 ]
Yu, Chang Ho [4 ]
Turyk, Mary E. [5 ]
Black, Kathleen [2 ]
Steinberg, Michael B. [6 ]
Fan, Zhihua [4 ]
Burgess, Jefferey L. [7 ]
机构
[1] Rutgers State Univ, Rutgers Sch Publ Hlth, Dept Biostat & Epidemiol, New Brunswick, NJ 08854 USA
[2] Rutgers State Univ, Rutgers Environm & Occupat Hlth Sci Inst, New Brunswick, NJ 08854 USA
[3] Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Miami, FL 33136 USA
[4] New Jersey Dept Hlth, Environm & Chem Lab Serv, Trenton, NJ 08628 USA
[5] Univ Illinois, Sch Publ Hlth, Chicago, IL 60612 USA
[6] Rutgers Robert Wood Johnson Med Sch, Dept Med, New Brunswick, NJ 08903 USA
[7] Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, Tucson, AZ 85724 USA
关键词
per-and polyfluoroalkyl substances (PFAS); volunteer firefighters; PFAS prevalence;
D O I
10.3390/ijerph18073730
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Background: Per-and polyfluoroalkyl substances (PFAS), are ubiquitous pollutants associated with adverse health outcomes. High PFAS levels have been demonstrated among career firefighters; less is known about PFAS levels among volunteer firefighters who comprise two-thirds of US firefighters. Methods: Volunteer fire department members completed a survey and provided blood samples. We calculated geometric means and 95% CIs for PFAS reported by the National Health and Nutrition Examination Survey (NHANES). We compared PFAS distribution and levels among non-Hispanic white adult male study participants to those in the 2015-2016 and 2017-2018 NHANES cycles. We assessed associations between PFAS serum levels and years of firefighting controlling demographics and occupation using linear regression. Results: Participant's average age was 46.6 years (sd. 17.1). Perfluorododecanoic acid (PFDoA) was detected in almost half study but <3% of NHANES participants; serum levels of PFDoA, perfluorononanoic acid (PFNA), and perfluorodecanoic acid (PFDA) were elevated among participants compared with NHANES. Serum levels of both PFDA and PFDoA were positively associated with years of firefighting. Conclusions: Volunteer firefighters may have a different serum profile and levels of PFAS than the general population. Future work in this area should include volunteer firefighters from other geographic locations and assess sources of PFAS exposure.
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页数:13
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