Therapeutic drug monitoring of antimicrobials

被引:17
作者
Balakrishnan, Indran [1 ,2 ]
Shorten, Robert J. [2 ,3 ]
机构
[1] Royal Free London NHS Fdn Trust, Dept Med Microbiol, London, England
[2] UCL, Ctr Clin Microbiol, Royal Free Campus, London, England
[3] Manchester Royal Infirm, Publ Hlth Lab Manchester, Oxford Rd, Manchester M13 9WL, Lancs, England
关键词
Antimicrobial therapy; therapeutic drug monitoring; ESCHERICHIA-COLI; DISSEMINATED CANDIDIASIS; ORAL POSACONAZOLE; BRITISH SOCIETY; AMPHOTERICIN-B; PHARMACOKINETICS; VORICONAZOLE; GENTAMICIN; VANCOMYCIN; SAFETY;
D O I
10.1177/0004563215618981
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
As pathology services become more centralized and automated, the measurement of therapeutic antimicrobial drugs concentrations is increasingly performed in clinical biochemistry or blood science' laboratories. This review outlines key groups of antimicrobial agents: aminoglycosides, glycopeptides, antifungal agents and antituberculosis agents, their role in managing infectious diseases, and the reasons why serum concentration measurement is important.
引用
收藏
页码:333 / 346
页数:14
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