Therapeutic drug monitoring of antimicrobials

被引：17
作者：
Balakrishnan, Indran [1 ,2 ]
Shorten, Robert J. [2 ,3 ]
机构：
[1] Royal Free London NHS Fdn Trust, Dept Med Microbiol, London, England
[2] UCL, Ctr Clin Microbiol, Royal Free Campus, London, England
[3] Manchester Royal Infirm, Publ Hlth Lab Manchester, Oxford Rd, Manchester M13 9WL, Lancs, England
来源：
ANNALS OF CLINICAL BIOCHEMISTRY | 2016年 / 53卷 / 03期
关键词：
Antimicrobial therapy; therapeutic drug monitoring; ESCHERICHIA-COLI; DISSEMINATED CANDIDIASIS; ORAL POSACONAZOLE; BRITISH SOCIETY; AMPHOTERICIN-B; PHARMACOKINETICS; VORICONAZOLE; GENTAMICIN; VANCOMYCIN; SAFETY;
D O I：
10.1177/0004563215618981
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
As pathology services become more centralized and automated, the measurement of therapeutic antimicrobial drugs concentrations is increasingly performed in clinical biochemistry or blood science' laboratories. This review outlines key groups of antimicrobial agents: aminoglycosides, glycopeptides, antifungal agents and antituberculosis agents, their role in managing infectious diseases, and the reasons why serum concentration measurement is important.
引用
收藏
页码：333 / 346
页数：14
相关论文
共 53 条
[1]   Therapeutic Drug Monitoring in the Treatment of Tuberculosis: An Update [J].
Alsultan, Abdullah ;
Peloquin, Charles A. .
DRUGS, 2014, 74 (08) :839-854
[2]   In vivo characterization of the pharmacodynamics of flucytosine in a neutropenic murine disseminated candidiasis model [J].
Andes, D ;
van Ogtrop, M .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (04) :938-942
[3]   Pharmacodynamics of a new triazole, posaconazole, in a murine model of disseminated candidiasis [J].
Andes, D ;
Marchillo, K ;
Conklin, R ;
Krishna, G ;
Ezzet, F ;
Cacciapuoti, A ;
Loebenberg, D .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (01) :137-142
[4]  
[Anonymous], 2014, British National Formulary N˚68
[5]  
[Anonymous], TUB CLIN DIAGN MAN T
[6]   Therapeutic drug monitoring (TDM) of antifungal agents: guidelines from the British Society for Medical Mycology [J].
Ashbee, H. Ruth ;
Barnes, Rosemary A. ;
Johnson, Elizabeth M. ;
Richardson, Malcolm D. ;
Gorton, Rebecca ;
Hope, William W. .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2014, 69 (05) :1162-1176
[7]   Therapeutic drug monitoring in the treatment of active tuberculosis [J].
Babalik, Aylin ;
Mannix, Sharyn ;
Francis, Denis ;
Menzies, Dick .
CANADIAN RESPIRATORY JOURNAL, 2011, 18 (04) :225-229
[8]   PHARMACOLOGICAL STUDIES WITH 5-FLUOROCYTOSINE [J].
BLOCK, ER ;
BENNETT, JE .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1972, 1 (06) :476-&
[9]   Clinical ototoxicity of teicoplanin [J].
Bonnet, RM ;
Mattie, H ;
De Laat, JAPM ;
Schoemaker, HC ;
Frijns, JHM .
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 2004, 113 (04) :310-312
[10]  
British Thoracic Society, 2014, UK BAS RES SUPP MON
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