Where To Begin? Mapping Transcription Start Sites Genome-Wide in Escherichia coli

被引：7
|
作者：
Wade, Joseph T. [1 ,2 ]
机构：
[1] New York State Dept Hlth, Wadsworth Ctr, Albany, NY 12205 USA
[2] SUNY Albany, Dept Biomed Sci, Albany, NY USA
来源：
JOURNAL OF BACTERIOLOGY | 2015年 / 197卷 / 01期
关键词：
ANTISENSE TRANSCRIPTION; RNA; BACTERIA;
D O I：
10.1128/JB.02410-14
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Recent genome-wide studies of bacterial transcription have revealed large numbers of promoters located inside genes. In this issue of the Journal of Bacteriology, Thomason and colleagues (J. Bacteriol. 197:18-28, 2015, doi:10.1128/JB.02096-14) map transcription start sites in Escherichia coli on an unprecedented scale. This work provides important insights into the regulation of transcripts that initiate inside genes and sources of variability between studies aimed at identifying these RNAs.
引用
收藏
页码：4 / 6
页数：3
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