HLA-G and HLA-E: fundamental and pathophysiological aspects

被引：101

作者：

Carosella, ED ^{[1
]}

Paul, P ^{[1
]}

Moreau, P ^{[1
]}

Rouas-Freiss, N ^{[1
]}

机构：

[1] Hop St Louis, DRM, DSV,IUH, Commissariat Energie Atom,Serv Rech Hematoimmunol, F-75475 Paris 10, France

来源：

IMMUNOLOGY TODAY | 2000年 / 21卷 / 11期

关键词：

D O I：

10.1016/S0167-5699(00)01707-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The First International Conference on HLA-G, held in 1998, led us to the conclusion that HLA-G is a tolerance molecule from the major histocompatibility complex (MHC) that plays an important role in maternal-fetal tolerance and probably in tumours and transplantation. The Second International Conference on HLA-G* focused on the pathophysiology of HLA-G and was extended to HLA-E and HLA-F.

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页码：532 / 534

页数：3

相关论文

共 8 条

[1] HLA-G: a tolerance molecule from the major histocompatibility complex [J].

Carosella, ED ;

Rouas-Freiss, N ;

Paul, P ;

Dausset, J .

IMMUNOLOGY TODAY, 1999, 20 (02) :60-62

[2] Soluble HLA-G1 triggers CD95/CD95 ligand-mediated apoptosis in activated CD8+ cells by interacting with CD8 [J].

Fournel, S ;

Aguerre-Girr, M ;

Huc, X ;

Lenfant, F ;

Alam, A ;

Toubert, A ;

Bensussan, A ;

Le Bouteiller, P .

JOURNAL OF IMMUNOLOGY, 2000, 164 (12) :6100-6104

[3] Implication of HLA-G molecule in heart-graft acceptance [J].

Lila, N ;

Carpentier, A ;

Amrein, C ;

Khalil-Daher, I ;

Dausset, J ;

Carosella, ED .

LANCET, 2000, 355 (9221) :2138-2138

[4] Modulation of HLA-G antigens expression by human cytomegalovirus:: Specific induction in activated macrophages harboring human cytomegalovirus infection [J].

Onno, M ;

Pangault, C ;

Le Friec, G ;

Guilloux, V ;

André, P ;

Fauchet, R .

JOURNAL OF IMMUNOLOGY, 2000, 164 (12) :6426-6434

[5]

Paul P, 1999, CANCER RES, V59, P1954

[6] The immunotolerance role of HLA-G [J].

Rouas-Freiss, N ;

Khalil-Daher, I ;

Riteau, B ;

Menier, C ;

Paul, P ;

Dausset, J ;

Carosella, ED .

SEMINARS IN CANCER BIOLOGY, 1999, 9 (01) :3-12

[7] Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis [J].

RouasFreiss, N ;

Goncalves, RMB ;

Menier, C ;

Dausset, J ;

Carosella, ED .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (21) :11520-11525

[8] Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40 [J].

Tomasec, P ;

Braud, VM ;

Rickards, C ;

Powell, MB ;

McSharry, BP ;

Gadola, S ;

Cerundolo, V ;

Borysiewicz, LK ;

McMichael, AJ ;

Wilkinson, GWG .

SCIENCE, 2000, 287 (5455) :1031-1033