It's a kar9ochore to capture microtubules

被引：45

作者：

Bloom, K ^{[1
]}

机构：

[1] Univ N Carolina, Dept Biol, Chapel Hill, NC 27599 USA

来源：

NATURE CELL BIOLOGY | 2000年 / 2卷 / 06期

关键词：

D O I：

10.1038/35014089

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Microtubule orientation to cortical spatial cues is essential for the fidelity of asymmetric cellular processes. A cortical microtubule-capture site, composed of Bim1 and Kar9, has now been identified in yeast. Bim1 is the yeast homologue of EB1, a binding partner of the adenomatous polyposis coli (APC), indicating that important features of this complex may be highly conserved.

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页码：E96 / E98

页数：3

相关论文

共 22 条

[1] Microtubule interactions with the cell cortex causing nuclear movements in Saccharomyces cerevisiae [J].

Adames, NR ;

Cooper, JA .

JOURNAL OF CELL BIOLOGY, 2000, 149 (04) :863-874

[2] Aip3p/Bud6p, a yeast actin-interacting protein that is involved in morphogenesis and the selection of bipolar budding sites [J].

Amberg, DC ;

Zahner, JE ;

Mulholland, JW ;

Pringle, JR ;

Botstein, D .

MOLECULAR BIOLOGY OF THE CELL, 1997, 8 (04) :729-753

[3] Localization and anchoring of mRNA in budding yeast [J].

Beach, DL ;

Salmon, ED ;

Bloom, K .

CURRENT BIOLOGY, 1999, 9 (11) :569-578

[4] Mal3, the fission yeast homologue of the human APC-interacting protein EB-1 is required for microtubule integrity and the maintenance of cell form [J].

Beinhauer, JD ;

Hagan, IM ;

Hegemann, JH ;

Fleig, U .

JOURNAL OF CELL BIOLOGY, 1997, 139 (03) :717-728

[5] Asymmetric accumulation of ASH1p in postanaphase nuclei depends on a myosin and restricts yeast mating-type switching to mother cells [J].

Bobola, N ;

Jansen, RP ;

Shin, TH ;

Nasmyth, K .

CELL, 1996, 84 (05) :699-709

[6] Movement of a cytokinesis factor cdcl2p to the site of cell division [J].

Chang, F .

CURRENT BIOLOGY, 1999, 9 (15) :849-852

[7] Bni1p, a yeast formin linking Cdc42p and the actin cytoskeleton during polarized morphogenesis [J].

Evangelista, M ;

Blundell, K ;

Longtine, MS ;

Chow, CJ ;

Adames, N ;

Pringle, JR ;

Peter, M ;

Boone, C .

SCIENCE, 1997, 276 (5309) :118-122

[8] Coronin promotes the rapid assembly and cross-linking of actin filaments and may link the actin and microtubule cytoskeletons in yeast [J].

Goode, BL ;

Wong, JJ ;

Butty, AC ;

Peter, M ;

McCormack, AL ;

Yates, JR ;

Drubin, DG ;

Barnes, G .

JOURNAL OF CELL BIOLOGY, 1999, 144 (01) :83-98

[9] The secretory pathway mediates localization of the cell polarity regulator Aip3p/Bud6p [J].

Jin, H ;

Amberg, DC .

MOLECULAR BIOLOGY OF THE CELL, 2000, 11 (02) :647-661

[10] Molecular linkage underlying microtubule orientation toward cortical sites in yeast [J].

Korinek, WS ;

Copeland, MJ ;

Chaudhuri, A ;

Chant, J .

SCIENCE, 2000, 287 (5461) :2257-2259