Unusual Histology in Mesothelioma: A Report of Two Cases with a Brief Review

被引：3

作者：

Bono, Francesca ^{[1
]}

Ceola, Stefano ^{[2
]}

Beretta, Carlo ^{[2
]}

Jaconi, Marta ^{[1
]}

机构：

[1] San Gerardo Hosp, Pathol Unit, I-20900 Monza, Italy

[2] Univ Milano Bicocca, San Gerardo Hosp, Dept Med & Surg Pathol, I-20900 Monza, Italy

来源：

DIAGNOSTICS | 2022年 / 12卷 / 02期

关键词：

mesothelioma; adenomatoid mesothelioma; signet ring cell mesothelioma; unusual variant epithelioid mesothelioma; EPITHELIOID PLEURAL MESOTHELIOMA; BAP1; MUTATIONS; DIAGNOSIS; PROGNOSIS; FISH;

D O I：

10.3390/diagnostics12020371

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Mesothelioma is often difficult to diagnose due to its rarity and its unusual histopathological features that could lend to diagnostic pitfalls and misdiagnosis. The WHO histological classification of pleural tumors in 2021 recommended a pathologic grading system for malignant pleural mesothelioma. Architectural aspects and cytological features, with nuclear grading, bent on a neoplastic score with fundamental prognostic and diagnostic value. Unusual features must be correctly assigned in the grading system to avoid misdiagnosis, especially toward metastatic lesions or reactive pleural processes. In this paper, we present two cases as examples of unusual morphological and architectural features with a brief literature review.

引用

页数：8

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