A Comprehensive Review of Sarcoidosis Diagnosis and Monitoring for the Pulmonologist

被引：10

作者：

Melani, Andrea S. ^{[1
]}

Simona, Albano ^{[1
]}

Armati, Martina ^{[2
]}

D'Alessandro, Miriana ^{[2
,3
]}

Bargagli, Elena ^{[2
,3
]}

机构：

[1] Azienda Osped Senese, UOS Pneumol UTIP, Dip Sci Med Chirurg & Neurosci, Policlin Le Scotte Viale Bracci, I-53100 Siena, Italy

[2] Univ Siena Policlin Le Scotte, UOC Malattie Resp, Dip Sci Med Chirurg & Neurosci, Siena, Italy

[3] Univ Siena Policlin Le Scotte, UOC Malattie Resp, Dip Sci Med Chirurg & Neurosci, Immunoallergol Rare Resp Dis & Lung Transplant La, Siena, Italy

来源：

PULMONARY THERAPY | 2021年 / 7卷 / 02期

关键词：

Sarcoidosis; Diagnosis; Monitoring; Biomarkers; Clinical evaluation; PULMONARY SARCOIDOSIS; RISK; QUESTIONNAIRE; VALIDATION; STATEMENT; UTILITY;

D O I：

10.1007/s41030-021-00161-w

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Sarcoidosis is a systemic granulomatous disease with heterogenous clinical manifestations. Here we review the diagnosis of sarcoidosis and propose a clinically feasible diagnostic work-up and monitoring protocol. As sarcoidosis is a systemic disease, a multidisciplinary approach is recommended for best outcomes. However, since the lungs are frequently involved, the pulmonologist is often the referral physician for diagnosis and management. When sarcoidosis is suspected, diagnosis needs to be confirmed and organ involvement/impairment assessed. This process is also required to establish whether the patient is likely to benefit from treatment, as many cases of sarcoidosis are self-limited and remit spontaneously. Whether or not treatment is started, effective regular follow-up is necessary to monitor changes in the disease, including extension, progression, remissions, flare-ups, and complications.

引用

页码：309 / 324

页数：16