Experimental and numerical analysis of blood flow in roughness impact-R test

被引:2
作者
Kopernik, Magdalena [1 ,3 ]
Kruczek, Dawid
Kurtyka, Przemyslaw [2 ]
Pomorska, Malgorzata [2 ]
Major, Roman [2 ]
机构
[1] AGH Univ Sci & Technol, Krakow, Poland
[2] Polish Acad Sci, Inst Met & Mat Sci, Krakow, Poland
[3] AGH Univ Sci & Technol, Al Mickiewicza 30, PL-30364 Krakow, Poland
关键词
finite volume method (FVM); disperse particle method (DPM); two-phase blood model; red blood cells (RBCs); impact-R; roughness; PLATE APPARATUS; CONE; ACTIVATION; CELLS; COAGULATION; DEPOSITION; RHEOLOGY; VESSELS; SURFACE; MODELS;
D O I
10.37190/ABB-02134-2022-02
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Purpose: The present paper covers simulation of blood flow in a roughness impact -R test model to anticipate the hemodynamic conditions of adhesion of blood elements to the modified surface. It was performed using numerical modelling of this process. The aim of these simulations was to create a surface morphology that stimulates the adhesion of blood elements to the surface of base plate of impact -R test. Methods: The morphology of base plate of impact -R test was developed using a vacuum powder sintering of commercial purity titanium powder (CP-Ti) on Ti6Al7Nb substrate. The finite volume method (FVM) and disperse particle method (DPM) were applied to develop the target model of a roughness impact -R test. The morphology of modified surfaces was documented with digital microscope and SEM (scanning electron microscopy). Results: The impact -R test developed using the two-phase blood model performed on regularly structured base plate resulted in shear stress values higher than the analogous for the model lacking such modification. The most significant reduction in maximum values of shear stress occurred in case of the DPM model and espe-cially in the model with regular structures. Conclusions: The proposed models are very effective in modeling of the analysis of blood flow in roughness impact -R test.
引用
收藏
页码:119 / 133
页数:15
相关论文
共 51 条
[1]  
ADAMCZUK K., 2016, CURR PROBL BIOMECH, V11, P9
[2]   Non-uniform distribution of myosin-mediated forces governs red blood cell membrane curvature through tension modulation [J].
Alimohamadi, Haleh ;
Smith, Alyson S. ;
Nowak, Roberta B. ;
Fowler, Velia M. ;
Rangamani, Padmini .
PLOS COMPUTATIONAL BIOLOGY, 2020, 16 (05)
[3]   Osteoinduction by Foamed and 3D-Printed Calcium Phosphate Scaffolds: Effect of Nanostructure and Pore Architecture [J].
Barba, Albert ;
Diez-Escudero, Anna ;
Maazouz, Yassine ;
Rappe, Katrin ;
Espanol, Montserrat ;
Montufar, Edgar B. ;
Bonany, Mar ;
Sadowska, Joanna M. ;
Guillern-Marti, Jordi ;
Ohman-Magi, Caroline ;
Persson, Cecilia ;
Manzanares, Maria-Cristina ;
Franch, Jordi ;
Ginebra, Maria-Pau .
ACS APPLIED MATERIALS & INTERFACES, 2017, 9 (48) :41722-41736
[4]   Microstructure and antibacterial properties of a ZnO coating on a biomaterial surface [J].
Basiaga, Marcin ;
Paszenda, Zbigniew ;
Lison, Julia ;
Taratuta, Anna ;
Kazek-Kesik, Alicja ;
Krok-Borkowicz, Malgorzata ;
Nuckowski, Pawel ;
Szindler, Magdalena ;
Staszuk, Marcin ;
Major, Lukasz ;
Major, Roman ;
Barabaszova, Karla Cech ;
Dyner, Marcin .
ARCHIVES OF CIVIL AND MECHANICAL ENGINEERING, 2022, 22 (02)
[5]   Recent advances in blood rheology: a review [J].
Beris, Antony N. ;
Horner, Jeffrey S. ;
Jariwala, Soham ;
Armstrong, Matthew J. ;
Wagner, Norman J. .
SOFT MATTER, 2021, 17 (47) :10591-10613
[6]   Effects of changes in packed cell volume on the specific heat capacity of blood: implications for studies measuring heat exchange in extracorporeal circuits [J].
Blake, AST ;
Petley, GW ;
Deakin, CD .
BRITISH JOURNAL OF ANAESTHESIA, 2000, 84 (01) :28-32
[8]   Analysis of flow in a cone-and-plate apparatus with respect to spatial and temporal effects on endothelial cells [J].
Buschmann, MH ;
Dieterich, P ;
Adams, NA ;
Schnittler, HJ .
BIOTECHNOLOGY AND BIOENGINEERING, 2005, 89 (05) :493-502
[9]   Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft [J].
Cai, Qingjin ;
Liao, Wanshan ;
Xue, Fangchao ;
Wang, Xiaochen ;
Zhou, Weiming ;
Li, Yanzhao ;
Zeng, Wen .
BIOACTIVE MATERIALS, 2021, 6 (08) :2557-2568
[10]   Fibroblast Interaction with Different Abutment Surfaces: In Vitro Study [J].
Canullo, Luigi ;
Genova, Tullio ;
Trujillo, Esperanza Gross ;
Pradies, Guillermo ;
Petrillo, Sara ;
Muzzi, Maurizio ;
Carossa, Stefano ;
Mussano, Federico .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (06)