Assisted Tandem Palladium(II)/Palladium(0)-Catalyzed C- and N-Arylations of Quinoxalin-2(1H)-ones in Water

被引：77
作者：
Carrer, Amandine [1 ]
Brion, Jean-Daniel [1 ]
Alami, Mouad [1 ]
Messaoudi, Samir [1 ]
机构：
[1] Univ Paris 11, CNRS, BioCIS UMR 8076, LabEx LERMIT,Fac Pharm,Lab Chim Therapeut,Equipe, F-92296 Chatenay Malabry, France
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2014年 / 356卷 / 18期
关键词：
assisted tandem catalysis; C-arylation; N-arylation; palladium catalysis; quinoxalinones; MULTIFUNCTIONAL PALLADIUM CATALYSIS; ZEROVALENT PALLADIUM; CLOSING METATHESIS; OLEFIN METATHESIS; COMPLEXES; TRANSFORMATIONS; PD(OAC)(2); REACTIVITY; CHEMISTRY; SEQUENCE;
D O I：
10.1002/adsc.201400662
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A straightforward assisted tandem palladium(II)- and palladium(0)-catalyzed direct C-3 and N-4 arylation of quinoxalin-2(1H)-ones with boronic acids and aryl halides in water as safe and cheap solvent is reported. This environmentally friendly catalytic protocol is compatible with a wide range of functional groups and allows construction of various biologically important quinoxalin-2(1H)-one backbones.
引用
收藏
页码：3821 / 3830
页数：10
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