COVID-19: A Review on the Novel Coronavirus Disease Evolution, Transmission, Detection, Control and Prevention

被引:386
作者
Sharma, Anshika [1 ]
Ahmad Farouk, Isra [1 ]
Lal, Sunil Kumar [1 ,2 ]
机构
[1] Monash Univ Malaysia, Sch Sci, Bandar Sunway 47500, Selangor De, Malaysia
[2] Monash Univ Malaysia, Trop Med & Biol Multidisciplinary Platform, Bandar Sunway 47500, Selangor De, Malaysia
来源
VIRUSES-BASEL | 2021年 / 13卷 / 02期
关键词
COVID-19; 2019-nCoV; emerging infectious disease; zoonotic cycle; positive-sense RNA viruses; evolution; NUCLEOCAPSID PROTEIN; SPIKE PROTEIN; SARS; REPLICATION; INFECTION; MODELS; ASSAY; NL63; COV;
D O I
10.3390/v13020202
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Three major outbreaks of the coronavirus, a zoonotic virus known to cause respiratory disease, have been reported since 2002, including SARS-CoV, MERS-CoV and the most recent 2019-nCoV, or more recently known as SARS-CoV-2. Bats are known to be the primary animal reservoir for coronaviruses. However, in the past few decades, the virus has been able to mutate and adapt to infect humans, resulting in an animal-to-human species barrier jump. The emergence of a novel coronavirus poses a serious global public health threat and possibly carries the potential of causing a major pandemic outbreak in the naive human population. The recent outbreak of COVID-19, the disease caused by SARS-CoV-2, in Wuhan, Hubei Province, China has infected over 36.5 million individuals and claimed over one million lives worldwide, as of 8 October 2020. The novel virus is rapidly spreading across China and has been transmitted to 213 other countries/territories across the globe. Researchers have reported that the virus is constantly evolving and spreading through asymptomatic carriers, further suggesting a high global health threat. To this end, current up-to-date information on the coronavirus evolution and SARS-CoV-2 modes of transmission, detection techniques and current control and prevention strategies are summarized in this review.
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