Cross-Coupling Reactions through the Intramolecular Activation of Alkyl(triorgano)silanes

被引：94

作者：

Nakao, Yoshiaki ^{[1
]}

Takeda, Masahide ^{[1
]}

Matsumoto, Takuya ^{[1
]}

Hiyama, Tamejiro ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Nishikyo Ku, Kyoto 6158510, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 26期

关键词：

copper; cross-coupling; palladium; silicon; ARYL HALIDES; CATALYZED 1,4-ADDITION; ALKYLZINC REAGENTS; GRIGNARD-REAGENTS; ORGANIC HALIDES; ALPHA-ARYLATION; SECONDARY; SILICON; DERIVATIVES; CHLORIDES;

D O I：

10.1002/anie.201000816

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Cross-Si-ing the Jordan: Cross-coupling reactions of 2-(2-hydroxyprop-2-yl)phenylsubstituted alkylsilanes with a variety of aryl halides proceed in the presence of palladium and copper catalysts. The use of K3PO4 base allows for highly chemoselective alkyl coupling with both primary and secondary alkyl groups (Alk). © 2010 WIley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：4447 / 4450

页数：4

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