Carbocupration of 1-alkynylphosphines followed by trapping with electrophiles

被引：18

作者：

Kanemura, Shigenari ^{[1
]}

Kondoh, Azusa ^{[1
]}

Yorimitsu, Hideki ^{[1
]}

Oshima, Koichiro ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Nishikyo Ku, Kyoto 6158510, Japan

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 10期

关键词：

D O I：

10.1021/ol0706657

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of 1-alkynylphosphine with magnesium dialkylcuprate in ether results in regio- and stereoselective syn- carbocupration. The alkenylcopper intermediate reacts with electrophile, which leads to allylation, acylation, and phosphination. The phosphination offers a new route to gem-diphosphinoalkene, an interesting phosphorus-based organic structure.

引用

页码：2031 / 2033

页数：3

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