Effect of bilateral stimulation of the subthalamic nucleus on parkinsonian dysarthria

被引：68

作者：

Gentil, M ^{[1
]}

Pinto, S ^{[1
]}

Pollak, P ^{[1
]}

Benabid, AL ^{[1
]}

机构：

[1] CHU Grenoble, INSERM, Unit 318, F-38043 Grenoble 9, France

来源：

BRAIN AND LANGUAGE | 2003年 / 85卷 / 02期

关键词：

Parkinson's disease; surgical treatment; subthalamic stimulation; speech; voice; acoustic analysis;

D O I：

10.1016/S0093-934X(02)00590-4

中图分类号：

R36 [病理学]; R76 [耳鼻咽喉科学];

学科分类号：

100104 ; 100213 ;

摘要：

Never was the effect of bilateral stimulation of the subthalamic nucleus (STN) evaluated quantitatively on all the components of speech production, that is articulation, respiration and phonation, at the same time. It is the purpose of this study which uses force measurements of the articulatory organs and acoustic analysis in 16 parkinsonian patients. With STN stimulation, reaction and movement time of the articulatory organs decreased and their maximal strength, as well as their precision increased. We also noted a large beneficial effect on voice with a significant improvement in respiratory and phonatory functions. (C) 2002 Elsevier Science (USA). All rights reserved.

引用

页码：190 / 196

页数：7

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