Impact of laparoscopic right hemicolectomy for colon cancer

被引:22
作者
Abdel-Halim, M. R. E.
Moore, H. M.
Cohen, P. [2 ]
Dawson, P.
Buchanan, G. N. [1 ]
机构
[1] Charing Cross Hosp, Imperial Coll Healthcare NHS Trust, Dept Colorectal Surg, London W6 8RF, England
[2] Charing Cross Hosp, Dept Histopathol, London W6 8RF, England
关键词
Colorectal cancer; Laparoscopic colectomy; Right hemicolectomy; OPEN COLECTOMY; SURGERY; RESECTION; CARCINOMA; RECOVERY; OUTCOMES; TRIAL;
D O I
10.1308/003588410X12628812458699
中图分类号
R61 [外科手术学];
学科分类号
摘要
INTRODUCTION This study specifically examined right colonic cancer resection, a common operation for colorectal surgeons starting laparoscopic resection, to assess the impact of commencing laparoscopy. PATIENTS AND METHODS A total of 56 patients undergoing open (n = 34) and attempted laparoscopic (n = 22) elective right hemicolectomy for colorectal cancer between November 2003 and March 2007 were compared. Postoperative stay was the primary outcome. Secondary outcomes included analgesic requirements, bowel recovery, morbidity and mortality. Frequency of laparoscopic versus open surgery over time was also examined. RESULTS Resections attempted laparoscopically increased from 9.1% to 75% in the first and last quarters of the study period, respectively (P=0.0002). Uptake of 'enhanced recovery' was mainly in the laparoscopic group. Conversion was required in two of 22 patients. Attempted laparoscopic cases had a shorter median postoperative stay (6 vs 10 days; P<0.0001), duration of parenteral or epidural analgesia (48 vs 72 h; P<0.0001) and time to first bowel action (3 vs 4 days; P=0.001) compared with open cases. Demography, tumour characteristics, morbidity and mortality were comparable between groups. Multivariate analysis identified decreased age, attempted laparoscopic surgery, use of enhanced recovery and absence of complications as independently shortening postoperative stay. CONCLUSIONS Advantages of laparoscopic surgery and enhanced recovery, even early in a surgeon's experience, suggest this is the preferred mode for elective right colon cancer resection.
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收藏
页码:211 / 217
页数:7
相关论文
共 29 条
[1]   Technique and survival after laparoscopically assisted right hemicolectomy [J].
Baca, I ;
Perko, Z ;
Bokan, I ;
Mimica, Z ;
Petricevic, A ;
Druzijanic, N ;
Situm, M .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2005, 19 (05) :650-655
[2]   A case-control study of laparoscopic right hemicolectomy vs. open right hemicolectomy [J].
Baker, RP ;
Titu, LV ;
Hartley, JE ;
Lee, PWR ;
Monson, JRT .
DISEASES OF THE COLON & RECTUM, 2004, 47 (10) :1675-1679
[3]   A clinical pathway to accelerate recovery after colonic resection [J].
Basse, L ;
Jakobsen, DH ;
Billesbolle, P ;
Werner, M ;
Kehlet, H .
ANNALS OF SURGERY, 2000, 232 (01) :51-57
[4]   MUST EARLY POSTOPERATIVE ORAL INTAKE BE LIMITED TO LAPAROSCOPY [J].
BINDEROW, SR ;
COHEN, SM ;
WEXNER, SD ;
NOGUERAS, JJ .
DISEASES OF THE COLON & RECTUM, 1994, 37 (06) :584-589
[5]   Laparoscopic surgery - 15 years after clinical introduction [J].
Bittner, Reinhard .
WORLD JOURNAL OF SURGERY, 2006, 30 (07) :1190-1203
[6]   Morbidity and mortality following laparoscopic-assisted right hemicolectomy for cancer [J].
Bokey, EL ;
Moore, JWE ;
Chapuis, PH ;
Newland, RC .
DISEASES OF THE COLON & RECTUM, 1996, 39 (10) :S24-S28
[7]   Laparoscopic surgery versus open surgery for colon cancer:: short-term outcomes of a randomised trial [J].
Bonjer, HJ ;
Haglind, E ;
Jeekel, I ;
Kazemier, G ;
Páhlman, L ;
Hop, WCJ ;
Veldkamp, R ;
Kuhry, E ;
Haglind, E ;
Pahlman, L ;
Cuesta, MA ;
Msika, S ;
Morino, M ;
Lacy, A ;
Jeekel, I .
LANCET ONCOLOGY, 2005, 6 (07) :477-484
[8]   Laparoscopic resection for colorectal cancer [J].
Buchanan, G. N. ;
Malik, A. ;
Parvaiz, A. ;
Sheffield, J. P. ;
Kennedy, R. H. .
BRITISH JOURNAL OF SURGERY, 2008, 95 (07) :893-902
[9]  
Del Rio P, 2006, Minerva Chir, V61, P293
[10]   Histone deposition proteins: Links between the DNA replication machinery and epigenetic gene silencing [J].
Franco, AA ;
Kaufman, PD .
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 2004, 69 :201-208