Boric acid catalyzed thia-Michael reactions in water or alcohols

被引：62

作者：

Chaudhuri, Mihir K. ^{[1
]}

Hussain, Sahid ^{[1
]}

机构：

[1] Indian Inst Technol Guwahati, Dept Chem, Gauhati 781039, India

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2007年 / 269卷 / 1-2期

关键词：

Michael addition; thiols; alpha; beta-unsaturated olefins; boric acid;

D O I：

10.1016/j.molcata.2007.01.014

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Boric acid acts as an efficient catalyst for the conjugate addition of aliphatic thiols, dithiols and aromatic thiols to alpha,beta-unsaturated nitriles, esters, ketones and aldehydes with very good yields in water at room temperature. The reactions are faster in MeOH or EtOH. The use of boric acid, being a safe chemical, as the catalyst and water as the reaction medium are important attributes in the present protocol. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：214 / 217

页数：4

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