An enantioselective chiral bronsted acid catalyzed imino-azaenamine reaction

被引：101
作者：
Rueping, Magnus
Sugiono, Erli
Theissmann, Thomas
Kuenkel, Alexander
Koeckritz, Angela
Pews-Davtyan, Anahit
Nemati, Navid
Beller, Matthias
机构：
[1] Goethe Univ Frankfurt, Inst Chem & Chem Biol, D-60438 Frankfurt, Germany
[2] Leibniz Inst Catalysis, D-18059 Rostock, Germany
来源：
ORGANIC LETTERS | 2007年 / 9卷 / 06期
关键词：
D O I：
10.1021/ol063112p
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The enantioselective Bronsted acid catalyzed addition of methyleneaminopyrrolidine to N-Boc imines has been achieved in the presence of chiral phosphoric acids derived from 3,3'-di(phenanthryl)-H8-BINOL. The corresponding aminohydrazones have been isolated in good yields with enantiomeric excesses up to 90%.
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页码：1065 / 1068
页数：4
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