The osseointegration rate of titanium dental implants is related to their composition and surface roughness. Rough-surfaced implants favor both bone anchoring and biomechanical stability. Osteoconductive calcium phosphate coatings promote bone healing and apposition, leading to the rapid biological fixation of implants. The different methods used for increasing surface roughness or applying osteoconductive coatings to titanium dental implants are reviewed. Surface treatments, such as titanium plasma-spraying, grit-blasting, acid-etching, anodization or calcium phosphate coatings, and their corresponding surface morphologies and properties are described. Most of these surfaces are commercially available and have proven clinical efficacy (>95% over 5 years). The precise role of surface chemistry and topography on the early events in dental implant osseointegration remain poorly understood. In addition, comparative clinical studies with different implant surfaces are rarely performed. The future of dental implantology should aim to develop surfaces with controlled and standardized topography or chemistry. This approach will be the only way to understand the interactions between proteins, cells and tissues, and implant surfaces. The local release of bone stimulating or resorptive drugs in the peri-implant region may also respond to difficult clinical situations with poor bone quality and quantity These therapeutic strategies should ultimately enhance the osseointegration process of dental implants for their immediate loading and long-term success. (C) 2006 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.
机构:
Xian Univ Architecture & Technol, Sch Met Engn, 13 Yanta Rd, Xian 710055, Peoples R ChinaXian Univ Architecture & Technol, Sch Met Engn, 13 Yanta Rd, Xian 710055, Peoples R China
Wang, Qingge
Zhou, Peng
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Xian Aeronaut Polytech Inst, Sch Aeronaut Mat Engn, Xian 710089, Peoples R ChinaXian Univ Architecture & Technol, Sch Met Engn, 13 Yanta Rd, Xian 710055, Peoples R China
Zhou, Peng
Liu, Shifeng
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Xian Univ Architecture & Technol, Sch Met Engn, 13 Yanta Rd, Xian 710055, Peoples R ChinaXian Univ Architecture & Technol, Sch Met Engn, 13 Yanta Rd, Xian 710055, Peoples R China
Liu, Shifeng
Attarilar, Shokouh
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Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R ChinaXian Univ Architecture & Technol, Sch Met Engn, 13 Yanta Rd, Xian 710055, Peoples R China
Attarilar, Shokouh
Ma, Robin Lok-Wang
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Hong Kong Univ Sci & Technol, Dept Mech & Aerosp Engn, Hong Kong 999077, Peoples R ChinaXian Univ Architecture & Technol, Sch Met Engn, 13 Yanta Rd, Xian 710055, Peoples R China
Ma, Robin Lok-Wang
Zhong, Yinsheng
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Hong Kong Univ Sci & Technol, Dept Mech & Aerosp Engn, Hong Kong 999077, Peoples R ChinaXian Univ Architecture & Technol, Sch Met Engn, 13 Yanta Rd, Xian 710055, Peoples R China
Zhong, Yinsheng
Wang, Liqiang
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Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R China
Natl Engn Res Ctr Nanotechnol NERCN, 28 East JiangChuan Rd, Shanghai 200241, Peoples R ChinaXian Univ Architecture & Technol, Sch Met Engn, 13 Yanta Rd, Xian 710055, Peoples R China
机构:
Kyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South Korea
George Washington Univ, Dept Mech & Aerosp Engn, Washington, DC 20052 USAKyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South Korea
Heo, Dong Nyoung
Ko, Wan-Kyu
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Kyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South KoreaKyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South Korea
Ko, Wan-Kyu
Lee, Hak Rae
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Korea Adv Inst Sci & Technol, Dept Chem & Biomol Engn, Daejeon 305701, South Korea
Korea Adv Inst Sci & Technol, KI Nano Century, Daejeon 305701, South KoreaKyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South Korea
Lee, Hak Rae
Lee, Sang Jin
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Kyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South KoreaKyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South Korea
Lee, Sang Jin
Lee, Donghyun
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Kyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South KoreaKyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South Korea
Lee, Donghyun
Um, Soong Ho
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Sungkyunlcwan Univ, Sch Chem Engn, Suwon 440746, Gyeonggi Do, South Korea
Sungkyunlcwan Univ, SKKU Adv Inst Nanotechnol, Suwon 440746, Gyeonggi Do, South KoreaKyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South Korea
Um, Soong Ho
Lee, Jung Haeng
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Kyung Hee Univ, Sch Dent, Dept Prosthodont, Seoul 130701, South KoreaKyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South Korea
Lee, Jung Haeng
Woo, Yi-Hyung
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Kyung Hee Univ, Sch Dent, Dept Prosthodont, Seoul 130701, South KoreaKyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South Korea
Woo, Yi-Hyung
Zhang, Lijie Grace
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George Washington Univ, Dept Mech & Aerosp Engn, Washington, DC 20052 USAKyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South Korea
Zhang, Lijie Grace
Lee, Deok-Won
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Kyung Hee Univ, Dept Oral & Maxillofacial Surg, Dent Hosp Gang Dong, Seoul 134727, South KoreaKyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South Korea
Lee, Deok-Won
Kwon, Il Keun
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Kyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South KoreaKyung Hee Univ, Sch Dent, Dept Dent Mat, Seoul 130701, South Korea
机构:
Univ Alcala, Dept Med & Med Specialties, Fac Med & Hlth Sci, Madrid 28871, SpainUniv Alcala, Dept Med & Med Specialties, Fac Med & Hlth Sci, Madrid 28871, Spain
Aragoneses, Javier
Lopez Valverde, Nansi
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Univ Alcala, Dept Med & Med Specialties, Fac Med & Hlth Sci, Madrid 28871, SpainUniv Alcala, Dept Med & Med Specialties, Fac Med & Hlth Sci, Madrid 28871, Spain
Lopez Valverde, Nansi
Fernandez-Dominguez, Manuel
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CEU San Pablo Univ, Dept Translat Med, Madrid 28660, SpainUniv Alcala, Dept Med & Med Specialties, Fac Med & Hlth Sci, Madrid 28871, Spain
Fernandez-Dominguez, Manuel
Mena-Alvarez, Jesus
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Univ Alfonso X El Sabio, Fac Dent, C Emilio Munoz 13, Madrid 28691, SpainUniv Alcala, Dept Med & Med Specialties, Fac Med & Hlth Sci, Madrid 28871, Spain
Mena-Alvarez, Jesus
Rodriguez, Cinthia
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Univ Federico Henriquez & Carvajal, Dept Dent, Santo Domingo 10106, Dominican RepUniv Alcala, Dept Med & Med Specialties, Fac Med & Hlth Sci, Madrid 28871, Spain
Rodriguez, Cinthia
Gil, Javier
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Univ Int Catalunya, Fac Med & Ciencias Salud, Bioengn Inst Technol, Sant Cugat Del Valles 08195, SpainUniv Alcala, Dept Med & Med Specialties, Fac Med & Hlth Sci, Madrid 28871, Spain
Gil, Javier
Manuel Aragoneses, Juan
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Univ Alfonso X El Sabio, Fac Dent, C Emilio Munoz 13, Madrid 28691, SpainUniv Alcala, Dept Med & Med Specialties, Fac Med & Hlth Sci, Madrid 28871, Spain
机构:
Pontificia Univ Catolica Rio Grande do Sul, Sch Hlth & Life Sci, Dent Dept, Porto Alegre, RS, Brazil
Pontificia Univ Catolica Rio Grande do Sul, Mat & Nanosci Lab, Porto Alegre, RS, BrazilPontificia Univ Catolica Rio Grande do Sul, Sch Hlth & Life Sci, Dent Dept, Porto Alegre, RS, Brazil
Kunrath, Marcel F.
Hubler, Roberto
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Pontificia Univ Catolica Rio Grande do Sul, Mat & Nanosci Lab, Porto Alegre, RS, BrazilPontificia Univ Catolica Rio Grande do Sul, Sch Hlth & Life Sci, Dent Dept, Porto Alegre, RS, Brazil
Hubler, Roberto
Silva, Raquel M.
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Univ Catolica Portuguesa, Ctr Interdisciplinary Res Hlth, Fac Dent Med, Viseu, PortugalPontificia Univ Catolica Rio Grande do Sul, Sch Hlth & Life Sci, Dent Dept, Porto Alegre, RS, Brazil
Silva, Raquel M.
Barros, Marlene
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Univ Catolica Portuguesa, Ctr Interdisciplinary Res Hlth, Fac Dent Med, Viseu, PortugalPontificia Univ Catolica Rio Grande do Sul, Sch Hlth & Life Sci, Dent Dept, Porto Alegre, RS, Brazil
Barros, Marlene
Teixeira, Eduardo R.
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Pontificia Univ Catolica Rio Grande do Sul, Sch Hlth & Life Sci, Dent Dept, Porto Alegre, RS, BrazilPontificia Univ Catolica Rio Grande do Sul, Sch Hlth & Life Sci, Dent Dept, Porto Alegre, RS, Brazil
Teixeira, Eduardo R.
Correia, Andre
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Univ Catolica Portuguesa, Ctr Interdisciplinary Res Hlth, Fac Dent Med, Viseu, PortugalPontificia Univ Catolica Rio Grande do Sul, Sch Hlth & Life Sci, Dent Dept, Porto Alegre, RS, Brazil