Substituent effects on the regioselectivity in fluorination of allylic alcohols with DAST

被引：35
|
作者：
Boukerb, A
Gree, D
Laabassi, M
Gree, R
机构：
[1] Ecole Natl Super Chim Rennes, CNRS, Lab Synth & Activat Biomol, F-35700 Rennes, France
[2] Univ Batna, Fac Sci, Batna, Algeria
来源：
JOURNAL OF FLUORINE CHEMISTRY | 1998年 / 88卷 / 01期
关键词：
DAST; fluorination; allylic systems; regioselectivity; fluorine NMR;
D O I：
10.1016/S0022-1139(98)00115-8
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The regioselectivity of the fluorination of various allylic and beta-dienoic alcohols with DAST has been studied. Substituent effects are important in these reactions; a strong preference for the secondary fluorides versus the primary ones is observed, especially in the case of alkyl and aryl substituted derivatives. (C) 1998 Elsevier Science S.A.
引用
收藏
页码：23 / 27
页数：5
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