Ring-Opening 1,3-Dichlorination of Donor-Acceptor Cyclopropanes by Iodobenzene Dichloride

被引：105

作者：

Garve, Lennart K. B. ^{[1
]}

Barkawitz, Philip ^{[1
]}

Jones, Peter G. ^{[1
]}

Werz, Daniel B. ^{[1
]}

机构：

[1] Tech Univ Carolo Wilhelmina Braunschweig, Inst Organ Chem, D-38106 Braunschweig, Germany

来源：

ORGANIC LETTERS | 2014年 / 16卷 / 21期

关键词：

SUBSTITUTED CYCLOPROPANES; 3+2 CYCLOADDITION; 1,2-CYCLOPROPANATED SUGARS; ASYMMETRIC-SYNTHESIS; AMINOCYCLOPROPANES; ALDEHYDES; ANNULATION; FURAN; TETRAHYDROFURANS; REARRANGEMENTS;

D O I：

10.1021/ol5029139

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Donor-acceptor cyclopropanes are reacted with iodobenzene dichloride to afford ring-opened products bearing chlorine atoms in the 1- and 3-positions, adjacent to the donor and acceptor groups. A variety of different donors (e.g., alkyl, aryl, N, and O) and acceptor moieties (e.g., ketones, diesters, and dinitriles) are used.

引用

页码：5804 / 5807

页数：4

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