Long-Term Follow-Up After Nonurgent Percutaneous Coronary Intervention in Unprotected Left Main Coronary Arteries

被引:4
作者
Beijk, Marcel A. M. [1 ]
Rittersma, Saskia Z. H. [1 ]
Koch, Karel T. [1 ]
Henriques, Jose P. S. [1 ]
Baan, Jan [1 ]
Vis, Marije M. [1 ]
Hoekstra, Fokje [1 ]
Tijssen, Jan G. P. [1 ]
Piek, Jan J. [1 ]
Kloek, Jaap J. [2 ]
de Mol, Bas A. J. M. [2 ]
de Winter, Robbert J. [1 ]
机构
[1] Univ Amsterdam, Acad Med Ctr, Dept Cardiol, NL-1105 AZ Amsterdam, Netherlands
[2] Univ Amsterdam, Acad Med Ctr, Dept Cardiothorac Surg, NL-1105 AZ Amsterdam, Netherlands
关键词
unprotected left main coronary artery; stenosis; percutaneous coronary intervention; stents; ELUTING STENT IMPLANTATION; LEFT-VENTRICULAR FUNCTION; BARE-METAL STENTS; CLINICAL-OUTCOMES; TASK-FORCE; STENOSIS; DISEASE; REVASCULARIZATION; IMMEDIATE; RISK;
D O I
10.1002/ccd.22404
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: To evaluate the long-term outcomes of the selected patients by the local Heart Team to undergo percutaneous coronary intervention (PCI) of unprotected left main coronary artery (ULMCA) stenosis and to compare patients considered at low surgical risk versus at high surgical risk for coronary artery bypass grafting (CABG). Background: CABG is recommended in patients with ULMCA stenosis according to the AHA/ACC and ESC guidelines, and there are limited data on the long-term outcomes in patients selected by the local Heart Team to undergo PCI. Methods: Between 1996 and 2007, 227 patients underwent PCI for ULMCA stenosis based on decision of the local Heart Team and patient's and/or physician's preference. All patients were contacted at 1 year and in November 2008. Results: Long-term follow-up was up to 8 years with a mean of 3.9 +/- 2.6 years. Overall, the Kaplan-Meier estimate of the composite of cardiac death, myocardial infarction (MI), or target lesion revascularization (TLR) was 14.8% at 1 year, 18.3% at 3 years, and 20.9% at 5 years with no events occurring thereafter. Patients considered at low surgical risk for CABG had a significantly lower incidence of cardiac death or MI compared to patients considered at high surgical risk at 8 years (1.4 vs. 16.8%; 1.4 vs. 14.8%, respectively); however, no significant difference was observed for cardiac death, MI, or TLR (18.6 vs. 24.4%). Conclusions: PCI of ULMCA stenosis in patients selected by the Heart Team resulted in good long-term clinical outcomes with most events occurring within the 1st year. Patients considered at low surgical risk for CABG have a significantly better long-term survival than patients at high risk for surgery. (C) 2010 Wiley-Liss, Inc.
引用
收藏
页码:1026 / 1036
页数:11
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