Synthesis of a novel pyrene-containing nucleoside and its incorporation into oligonucleotides

被引：12

作者：

Frazer, JD ^{[1
]}

Horner, SM ^{[1
]}

Woski, SA ^{[1
]}

机构：

[1] Univ Alabama, Dept Chem, Tuscaloosa, AL 35487 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 11期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0040-4039(97)10853-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of the aryl nucleoside analogue beta-2'-deoxy-D-ribofuranosyl-1'-N-pyrenyl-carboxamide (4) is described. This compound can be converted into a phosphoramidite reagent and used in solid phase oligonucleotide synthesis. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：1279 / 1282

页数：4

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