The potential role of podoplanin in tumour invasion

被引：243
|
作者：
Wicki, A. [1 ]
Christofori, G. [1 ]
机构：
[1] Univ Basel, Dept Clin Biol Sci, Inst Biochem & Genet, Ctr Biomed, CH-4058 Basel, Switzerland
来源：
BRITISH JOURNAL OF CANCER | 2007年 / 96卷 / 01期
关键词：
cadherin; cancer; cytoskeleton; EMT; invasion; podoplanin;
D O I：
10.1038/sj.bjc.6603518
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Podoplanin is a small mucin-like transmembrane protein, widely expressed in various specialised cell types throughout the body. Here, we revisit the mechanism of podoplanin-mediated tumour invasion. We compare molecular pathways leading to single and collective cell invasion and discuss novel distinct concepts of tumour cell invasion.
引用
收藏
页码：1 / 5
页数：5
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