Synthesis and antimicrobial activity of novel spirocompounds with pyrazolone and pyrazolthione moiety

被引：153

作者：

Chande, Madhukar S. ^{[1
]}

Barve, Pravin A. ^{[1
]}

Suryanarayan, Vijay ^{[1
]}

机构：

[1] Inst Sci, Dept Chem, Bombay 400032, Maharashtra, India

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2007年 / 44卷 / 01期

关键词：

D O I：

10.1002/jhet.5570440108

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The paper focuses on the utility of 2-pyrazoline-5-ones and 2-pyrazoline-5-thiones as active Michael donors for the synthesis of novel spirocyclohexanone derivatives. The sulphur containing compounds when screened for antimicrobial activity showed promising inhibition of S. Typhi, S Aures and E Coli bacteria.

引用

页码：49 / 53

页数：5

共 26 条

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