Phenolic glycosides from Symplocos racemosa:: natural inhibitors of phosphodiesterase I

被引：66

作者：

Ahmad, VU ^{[1
]}

Abbasi, MA ^{[1
]}

Hussain, H ^{[1
]}

Akhtar, MN ^{[1
]}

Farooq, U ^{[1
]}

Fatima, N ^{[1
]}

Choudhary, MI ^{[1
]}

机构：

[1] Univ Karachi, Int Ctr Chem Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan

来源：

PHYTOCHEMISTRY | 2003年 / 63卷 / 02期

关键词：

Symplocos racemosa Roxb; Symplocaceae; phenolic glycosides; phosphodiesterase I;

D O I：

10.1016/S0031-9422(03)00075-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

One new phenolic glycoside named benzoylsalireposide (1) along with one known phenolic glycoside named salireposide (2) have been isolated from Symplocos racemosa. Four other known compounds i.e. beta-amyrin (3), oleonolic acid (4), beta-sitosterol (5) and beta-sitosterol glycoside (6) were also isolated from this plant. The structure elucidation of the isolated compounds was based primarily on 1D- and 2D-NMR analysis, including COSY, HMQC, and HMBC correlations. The compound 1 and 2 showed inhibitory activity against snake venom phosphodiesterase I. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：217 / 220

页数：4

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