Four New Nor-Diterpenoid Alkaloids from Aconitum brahypodum

被引：12
|
作者：
Shen, Yong [1 ,2 ]
Zuo, Ai-Xue [1 ,2 ]
Jiang, Zhi-Yong [1 ]
Zhang, Xue-Mei [1 ]
Wang, Hong-Ling [1 ,2 ]
Chen, Ji-Jun [1 ]
机构：
[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
[2] Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China
来源：
HELVETICA CHIMICA ACTA | 2010年 / 93卷 / 05期
关键词：
D O I：
10.1002/hlca.200900297
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Four new C(19)-nor-diterpenoid alkaloids, named brachyaconitines A-D (1-4), were isolated from the roots of Aconitum brachypodum DIELS. Their structures were elucidated as 3-O-acetyl-20-deethyl-20-formylacoitine (1), 3-O-acetyl-19,20-didehydro-20-deethylaconitine (2), 3-O-acetyl-8-de(acety-loxy)-7,8,17,20-tetradehydro-20-deethy1-7,17-secoaconitine (3), and 1-O-methylflavaconitine (4) by means of MS, IR, 1D- and 2D-NMR analysis. The structure of compound 1 was confirmed by an X-ray difraction experiment.
引用
收藏
页码：863 / 869
页数：7
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