Extraction, Structural Characterization, and Biological Functions of Lycium Barbarum Polysaccharides: A Review

被引:214
作者
Tian, Xiaojing [1 ,2 ]
Liang, Tisong [1 ,2 ]
Liu, Yuanlin [1 ,2 ]
Ding, Gongtao [1 ]
Zhang, Fumei [1 ,2 ]
Ma, Zhongren [1 ,2 ]
机构
[1] Northwest Minzu Univ, Biomed Res Ctr, China Malaysia Natl Joint Lab, Lanzhou 730124, Gansu, Peoples R China
[2] Northwest Minzu Univ, Coll Life Sci & Engn, Lanzhou 730124, Gansu, Peoples R China
基金
中国国家自然科学基金;
关键词
Lycium barbarum polysaccharides; structural characterization; antitumor activity; antioxidant activity; immune regulation; INDUCED OXIDATIVE STRESS; GOJI BERRY; IN-VITRO; PHYSICOCHEMICAL PROPERTIES; ANTIOXIDANT ACTIVITY; ALZHEIMERS-DISEASE; INDUCED DAMAGE; CELLS; FRUIT; INJURY;
D O I
10.3390/biom9090389
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Lycium barbarum polysaccharides (LBPs), as bioactive compounds extracted from L. barbarum L. fruit, have been widely explored for their potential health properties. The extraction and structural characterization methods of LBPs were reviewed to accurately understand the extraction method and structural and biological functions of LBPs. An overview of the biological functions of LBPs, such as antioxidant function, antitumor activity, neuroprotective effects, immune regulating function, and other functions, were summarized. This review provides an overview of LBPs and a theoretical basis for further studying and extending the applications of LBPs in the fields of medicine and food.
引用
收藏
页数:17
相关论文
共 128 条
[1]   A review of botanical characteristics, phytochemistry, clinical relevance in efficacy and safety of Lycium barbarum fruit (Goji) [J].
Amagase, Harunobu ;
Farnsworth, Norman R. .
FOOD RESEARCH INTERNATIONAL, 2011, 44 (07) :1702-1717
[2]   Lycium barbarum (goji) juice improves in vivo antioxidant biomarkers in serum of healthy adults [J].
Amagase, Harunobu ;
Sun, Buxiang ;
Borek, Carmia .
NUTRITION RESEARCH, 2009, 29 (01) :19-25
[3]  
[Anonymous], DRUGS
[4]   Lycium barbarum Polysaccharide Improves Bipolar Pulse Current-Induced Microglia Cell Injury Through Modulating Autophagy [J].
Bie, Man ;
Lv, Yi ;
Ren, Chaoran ;
Xing, Feiyue ;
Cui, Qi ;
Xiao, Jia ;
So, Kwok Fai .
CELL TRANSPLANTATION, 2015, 24 (03) :419-428
[5]   Simple nanoliposomes encapsulating Lycium barbarum polysaccharides as adjuvants improve humoral and cellular immunity in mice [J].
Bo, Ruonan ;
Sun, Yaqin ;
Zhou, Shuzhen ;
Ou, Ning ;
Gu, Pengfei ;
Liu, Zhenguang ;
Hu, Yuanliang ;
Liu, Jiaguo ;
Wang, Deyun .
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2017, 12 :6289-6301
[6]   The immunological activity of Lycium barbarum polysaccharides liposome in vitro and adjuvanticity against PCV2 in vivo [J].
Bo, Ruonan ;
Zheng, Sisi ;
Xing, Jie ;
Luo, Li ;
Niu, Yale ;
Huang, Yee ;
Liu, Zhenguang ;
Hu, Yuanliang ;
Liu, Jiaguo ;
Wu, Yi ;
Wang, Deyun .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2016, 85 :294-301
[7]   Dietary natural products and lung cancer: Effects and mechanisms of action [J].
Cao, Shi-Yu ;
Li, Ya ;
Meng, Xiao ;
Zhao, Cai-Ning ;
Li, Sha ;
Gan, Ren-You ;
Li, Hua-Bin .
JOURNAL OF FUNCTIONAL FOODS, 2019, 52 :316-331
[8]   Lycium barbarum polysaccharide protects against neurotoxicity via the Nrf2-HO-1 pathway [J].
Cao, Shumei ;
Du, Jianlong ;
Hei, Qiaohong .
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2017, 14 (05) :4919-4927
[9]   Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases.: What do we know so far? [J].
Chang, Raymond Chuen-Chung ;
So, Kwok-Fai .
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2008, 28 (05) :643-652
[10]   Isolation, Characterization and Antitumor Effect on DU145 Cells of a Main Polysaccharide in Pollen of Chinese Wolfberry [J].
Chen, Fei ;
Ran, Linwu ;
Mi, Jia ;
Yan, Yamei ;
Lu, Lu ;
Jin, Bo ;
Li, Xiaoying ;
Cao, Youlong .
MOLECULES, 2018, 23 (10)