Exploiting poly(ethylene glycol) as a matrix for liquid-phase organic synthesis

被引：9
|
作者：
Sieber, F [1 ]
Wentworth, P [1 ]
Janda, KD [1 ]
机构：
[1] Scripps Res Inst, Res Inst, Skaggs Inst Chem Biol, Dept Chem, La Jolla, CA 92037 USA
来源：
MOLECULES | 2000年 / 5卷 / 08期
关键词：
soluble polymer; synthesis; poly(ethylene glycol); triphenyl phosphine; Wittig reaction; Stille reaction;
D O I：
10.3390/50801018
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Soluble polymer-supported chemistry is a technology that allows the blending of the benefits of polymer-supported synthesis and solution-phase chemistry. Herein, we describe our recent efforts in this area targeted at exploring the scope of poly(ethylene glycol) (PEG) as the matrix. Specifically we describe the use of PEG as a support for triphenyl phosphine and for the Stille reaction.
引用
收藏
页码：1018 / 1032
页数：15
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