Relationship of Neutrophil-Lymphocyte Ratio With the Presence, Severity, and Extent of Coronary Atherosclerosis Detected by Coronary Computed Tomography Angiography

被引:28
|
作者
Acar, Goksel [1 ]
Fidan, Serdar [1 ]
Uslu, Zulal Alnur [2 ]
Turkday, Sevim [1 ]
Avci, Anil [1 ]
Alizade, Elnur [1 ]
Kalkan, Mehmet Emin [1 ]
Tabakci, Omer Naci [3 ]
Tanboga, Ibrahim Halil [4 ]
Esen, Ali Metin [1 ]
机构
[1] Kartal Kosuyolu High Specialty Educ & Res Hosp, Dept Cardiol, TR-34846 Istanbul, Turkey
[2] Kartal Kosuyolu High Specialty Educ & Res Hosp, Dept Radiol, TR-34846 Istanbul, Turkey
[3] Sisli Etfal Educ & Res Hosp, Dept Radiol, Istanbul, Turkey
[4] Ataturk Univ, Dept Cardiol, Sch Med, Erzurum, Turkey
关键词
neutrophil-lymphocyte ratio; coronary atherosclerosis; computed tomography angiography; ELEVATION MYOCARDIAL-INFARCTION; LONG-TERM MORTALITY; ARTERY-DISEASE; CARDIAC EVENTS; HEART-DISEASE; INTERVENTION; ASSOCIATION; PREDICTOR; RISK;
D O I
10.1177/0003319714520954
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
We evaluated whether the neutrophil-lymphocyte ratio (NLR) was associated with the presence, severity, and extent of coronary atherosclerotic plaques detected by computed tomography angiography (CTA). We studied 238 patients who underwent dual-source 64-slice CTA for the assessment of coronary artery disease. Coronary arteries were evaluated on 16-segment basis and critical plaque was described as luminal narrowing >50%. In regression analysis, being in the third NLR tertile increased the risk of coronary atherosclerosis (odds ratio [OR], 2.30; 95% confidence interval [CI], 1.15-4.43; P = .023). When the severity of coronary atherosclerosis was assessed, being in the third NLR tertile increased the risk of critical luminal stenosis (OR, 2.60; 95% CI, 1.19-5.69; P = .017). Although plaque morphology was not associated with NLR, the extent of coronary atherosclerosis was increased with higher NLR tertiles (P = .001). Our results suggest that a higher NLR may be a useful additional measure to assess cardiovascular risk in clinical practice.
引用
收藏
页码:174 / 179
页数:6
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