Coagulopathy in two patients with cystic fibrosis treated with ciprofloxacin

被引:2
|
作者
Moore, Gillian C.
Redfern, Jan
Shiach, Caroline R.
Webb, Kevin
Jones, Andrew M.
机构
[1] Wythenshawe Hosp, NW Lung Ctr, Manchester Adult Cyst Fibrosis Unit, Manchester M23 9LT, Lancs, England
[2] Wythenshawe Hosp, Dept Haematol, Manchester M23 9LT, Lancs, England
关键词
cystic fibrosis; ciprofloxacin; coagulopathy; INR; APTT;
D O I
10.1016/j.jcf.2006.08.002
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
We report two cases of prolonged blood clotting times as demonstrated by a raised international normalised ratio and elevated activated partial thromboplastin time in patients with cystic fibrosis taking ciprofloxacin. The potential mechanisms of a coagulopathy of this picture as an adverse drug reaction with ciprofloxacin are discussed along with the possible clinical consequences for patients with cystic fibrosis. (C) 2006 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:209 / 211
页数:3
相关论文
共 50 条
  • [41] Lobectomy in patients with cystic fibrosis
    Sheikh, Shahid I.
    McCoy, Karen
    Ryan-Wenger, Nancy A.
    Patel, Alpa
    Kirkby, Stephen
    CANADIAN RESPIRATORY JOURNAL, 2014, 21 (04) : E63 - E66
  • [42] Proteinuria in patients with cystic fibrosis
    Kuwertz-Bröking, E
    Koch, HG
    Schulze-Everding, A
    Helmchen, U
    Bulla, M
    MONATSSCHRIFT KINDERHEILKUNDE, 1998, 146 (11) : 1044 - 1049
  • [43] MRSA in patients with cystic fibrosis
    Estrada, B
    INFECTIONS IN MEDICINE, 2004, 21 (01) : 13 - 13
  • [44] Mannitol-Guided Delivery of Ciprofloxacin in Artificial Cystic Fibrosis Mucus Model
    Yang, Yan
    Tsifansky, Michael D.
    Shin, Sooyoung
    Lin, Qingnuo
    Yeo, Yoon
    BIOTECHNOLOGY AND BIOENGINEERING, 2011, 108 (06) : 1441 - 1449
  • [45] Quality of life assessment in patients with cystic fibrosis by means of the Cystic Fibrosis Questionnaire
    Cohen, Milena Antonelli
    Goncalves de Oliveira Ribeiro, Maria Angela
    Ribeiro, Antonio Fernando
    Ribeiro, Jose Dirceu
    Morcillo, Andre Moreno
    JORNAL BRASILEIRO DE PNEUMOLOGIA, 2011, 37 (02) : 184 - 192
  • [46] Nebulisation therapy in patients with cystic fibrosis - consensus of the Polish Cystic Fibrosis Society
    Walicka-Serzysko, Katarzyna
    Orlik, Teresa
    Sands, Dorota
    Jeneralska, Natalia
    Popiel, Anna
    Skorupa, Wojciech
    Pogorzelski, Andrzej
    Cofta, Szczepan
    ADVANCES IN RESPIRATORY MEDICINE, 2021, 89 (06) : 570 - 580
  • [47] Biochemical assessment of the nutritional status of cystic fibrosis patients treated with pancreatic enzyme extracts
    Benabdeslam, H
    Garcia, I
    Bellon, G
    Gilly, R
    Revol, AE
    AMERICAN JOURNAL OF CLINICAL NUTRITION, 1998, 67 (05) : 912 - 918
  • [48] Acute pancreatitis in pancreatic-insufficient cystic fibrosis patients treated with CFTR modulators
    Sadras, Ido
    Cohen-Cymberknoh, Malena
    Kerem, Eitan
    Koplewitz, Benjamin Z.
    Simanovsky, Natalia
    Wilschanski, Michael
    Birimberg-Schwartz, Liron
    Breuer, Oded
    JOURNAL OF CYSTIC FIBROSIS, 2023, 22 (04) : 777 - 779
  • [49] Long term survival and nutritional data in patients with cystic fibrosis treated in a Danish centre
    Nir, M
    Lanng, S
    Johansen, HK
    Koch, C
    THORAX, 1996, 51 (10) : 1023 - 1027
  • [50] Pseudomonas aeruginosa and Burkholderia cepacia infection in cystic fibrosis patients treated in Toronto and Copenhagen
    Johansen, HK
    Kovesi, TA
    Koch, C
    Corey, M
    Hoiby, N
    Levison, H
    PEDIATRIC PULMONOLOGY, 1998, 26 (02) : 89 - 96