Fullerenes: From Carbon to Nanomedicine

被引：39

作者：

Chawla, Pooja ^{[2
]}

Chawla, Viney ^{[1
]}

Maheshwari, Radhika ^{[2
]}

Saraf, Shubhini A. ^{[2
]}

Saraf, Shailendra. K. ^{[1
]}

机构：

[1] No India Engn Coll, Fac Pharm, Lucknow 227105, Uttar Pradesh, India

[2] Babu Banarasi Das Natl Inst Technol & Management, Fac Pharm, Lucknow 227105, Uttar Pradesh, India

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2010年 / 10卷 / 08期

关键词：

Anti HIV; antioxidant; antiapoptotic; enzyme inhibition; nanomedicines; neuroprotective; ANTI-HIV PROPERTIES; FUNCTIONALIZED FULLERENES; AZOMETHINE YLIDES; HYDROGEN-PEROXIDE; DELIVERY-SYSTEMS; C-60; FULLERENE; AMINO-ACID; IN-VITRO; WATER; DERIVATIVES;

D O I：

10.2174/138955710791572497

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Fullerenes, the third carbon allotrope, have emerged as agents which could revolutionize the treatment of many diseases. Fullerenes possess different biological applications like neuroprotective agents, antioxidants, anti-HIV activity, enzyme inhibition, antiapoptotic activity and the list is ever increasing. Moreover, they are being utilized as drug carrier systems and also for many non-biological applications like superconductors, catalysis and so on. Their size has made them promising agents for nanotechnology. This article aims at outlining the chemistry, properties and non-biological applications of fullerenes and their evolution to biological applications, thereby traversing their evolution from simple carbon allotropes to present day nano-medicinal agents.

引用

页码：662 / 677

页数：16

共 135 条

[41] Blockage of apoptotic signaling of transforming growth factor-β in human hepatoma cells by carboxyfullerene [J].