A robust and recyclable ionic liquid-supported copper(II) catalyst for the synthesis of 5-substituted-1H-tetrazoles using microwave irradiation

被引:19
作者
Padmaja, R. D. [1 ]
Chanda, Kaushik [1 ]
机构
[1] Vellore Inst Technol, Sch Adv Sci, Dept Chem, Vellore 632014, Tamil Nadu, India
关键词
1H-tetrazoles; (3+2) cycloaddition; Microwave irradiation; Ionic liquid; 5-SUBSTITUTED; 1H-TETRAZOLES; 3+2 CYCLOADDITION; RECEPTOR ANTAGONISTS; EFFICIENT SYNTHESIS; NITRILES; TETRAZOLES; GREEN; NANOPARTICLES; POTENT;
D O I
10.1007/s11164-019-04035-4
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel and robust ionic liquid-supported copper(II) catalyst has been developed and explored for the efficient synthesis of 5-substituted-1H-tetrazoles using microwave irradiation. The ionic liquid-supported catalyst facilitated the efficient isolation of tetrazole products with high purity by simple extraction with organic solvent. Recovered ionic liquid-supported copper(II) catalyst could be recycled for three times for the synthesis of tetrazole products with high purity. This synthetic protocol offers a very clean, convenient, and microwave-assisted environment-friendly method for the efficient synthesis of 5-substituted-1H-tetrazoles with high yield.
引用
收藏
页码:1307 / 1317
页数:11
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