A robust and recyclable ionic liquid-supported copper(II) catalyst for the synthesis of 5-substituted-1H-tetrazoles using microwave irradiation

被引：19

作者：

Padmaja, R. D. ^{[1
]}

Chanda, Kaushik ^{[1
]}

机构：

[1] Vellore Inst Technol, Sch Adv Sci, Dept Chem, Vellore 632014, Tamil Nadu, India

来源：

RESEARCH ON CHEMICAL INTERMEDIATES | 2020年 / 46卷 / 02期

关键词：

1H-tetrazoles; (3+2) cycloaddition; Microwave irradiation; Ionic liquid; 5-SUBSTITUTED; 1H-TETRAZOLES; 3+2 CYCLOADDITION; RECEPTOR ANTAGONISTS; EFFICIENT SYNTHESIS; NITRILES; TETRAZOLES; GREEN; NANOPARTICLES; POTENT;

D O I：

10.1007/s11164-019-04035-4

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel and robust ionic liquid-supported copper(II) catalyst has been developed and explored for the efficient synthesis of 5-substituted-1H-tetrazoles using microwave irradiation. The ionic liquid-supported catalyst facilitated the efficient isolation of tetrazole products with high purity by simple extraction with organic solvent. Recovered ionic liquid-supported copper(II) catalyst could be recycled for three times for the synthesis of tetrazole products with high purity. This synthetic protocol offers a very clean, convenient, and microwave-assisted environment-friendly method for the efficient synthesis of 5-substituted-1H-tetrazoles with high yield.

引用

页码：1307 / 1317

页数：11

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