Antiinflammatory, Antioxidant, and Immunological Effects of Carum copticum L. and Some of Its Constituents

被引:24
作者
Alavinezhad, Azam [1 ]
Boskabady, Mohammad Hossein [1 ]
机构
[1] Mashhad Univ Med Sci, Sch Med, Dept Physiol, Neurogen Inflammat Res Ctr, Mashhad, Iran
关键词
Carum copticum; thymol; carvacrol; antiinflammatory; antioxidant; immunological effect; ZATARIA MULTIFLORA BOISS; FATTY-ACID-COMPOSITION; ESSENTIAL OIL; IN-VITRO; DIETARY SUPPLEMENTATION; ANTIMICROBIAL ACTIVITY; IMMUNE-RESPONSE; CARVACROL; THYMOL; RECEPTORS;
D O I
10.1002/ptr.5200
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Carum copticum L. has been used traditionally for its various therapeutic effects. The plant contains various components such as thymol and carvacrol. Different therapeutic effects such as antifungal, antioxidant, antibacterial, antiparasitic, and antilipidemic were described for the plant and its constituents. Therefore, antiinflammatory, antioxidant, and immunological effects of C.copticum and its constituents, thymol and carvacrol, were discussed in the present review. Previous studies have shown potent antiinflammatory, antioxidant, and immunological effects for C.copticum and its constituents, thymol and carvacrol. Therefore, the plant and its constituents have therapeutic values in several inflammatory and immunological disorders as well as in the oxidative stress conditions. Copyright (c) 2014 John Wiley & Sons, Ltd.
引用
收藏
页码:1739 / 1748
页数:10
相关论文
共 83 条
[1]   ANTIOXIDANT ACTIONS OF THYMOL, CARVACROL, 6-GINGEROL, ZINGERONE AND HYDROXYTYROSOL [J].
AESCHBACH, R ;
LOLIGER, J ;
SCOTT, BC ;
MURCIA, A ;
BUTLER, J ;
HALLIWELL, B ;
ARUOMA, OI .
FOOD AND CHEMICAL TOXICOLOGY, 1994, 32 (01) :31-36
[2]   In vitro immunomodulatory effects of extracts from three plants of the Labiatae family and isolation of the active compound(s) [J].
Amirghofran, Zahra ;
Hashemzadeh, Reihaneh ;
Javidnia, Katayoun ;
Golmoghaddam, Hossein ;
Esmaeilbeig, Ahmadreza .
JOURNAL OF IMMUNOTOXICOLOGY, 2011, 8 (04) :265-273
[3]   Carvacrol suppresses the expression of inflammatory marker genes in D-galactosamine-hepatotoxic rats [J].
Aristatile, Balakrishnan ;
Al-Assaf, Abdullah H. ;
Pugalendi, Kodukkur Viswanathan .
ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2013, 6 (03) :205-211
[4]   Effect of dietary supplementation of oregano essential oils to sows on colostrum and milk composition, growth pattern and immune status of suckling pigs [J].
Ariza-Nieto, C. ;
Bandrick, M. ;
Baidoo, S. K. ;
Anil, L. ;
Molitor, T. W. ;
Hathaway, M. R. .
JOURNAL OF ANIMAL SCIENCE, 2011, 89 (04) :1079-1089
[5]  
Bairwa Ranjan, 2012, Pharmacogn Rev, V6, P56, DOI 10.4103/0973-7847.95871
[6]  
Bekhechi C, 2010, NAT PROD COMMUN, V5, P1107
[7]  
Bentely R., 1983, MED PLANTS, V1
[8]   Novel natural antioxidant for stabilization of edible oil:: The ajowan (Carum copticum) extract case [J].
Bera, D ;
Lahiri, D ;
Nag, A .
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2004, 81 (02) :169-172
[9]   Evaluation of ophthacare® eye drops -: A herbal formulation in the management of various ophthalmic disorders [J].
Biswas, NR ;
Gupta, SK ;
Das, GK ;
Kumar, N ;
Mongre, PK ;
Haldar, D ;
Beri, S .
PHYTOTHERAPY RESEARCH, 2001, 15 (07) :618-620
[10]   The Effect of Carvacrol on Muscarinic Receptors of Guinea-pig Tracheal Chains [J].
Boskabady, M. H. ;
Jafari, Z. ;
Pouraboli, I. .
PHYTOTHERAPY RESEARCH, 2011, 25 (04) :530-535