Solid-phase synthesis of a modified 13-residue seminalplasmin fragment on 1,6-hexanediol diacrylate-crosslinked polystyrene support

被引：1

作者：

Arunan, C ^{[1
]}

Naaraj, R

Pillai, VNR

机构：

[1] Mahatma Gandhi Univ, Sch Chem Sci, Kottayam 686560, Kerala, India

[2] Ctr Cellular & Mol Biol, Hyderabad 500007, Andhra Pradesh, India

来源：

PEPTIDES | 2000年 / 21卷 / 06期

关键词：

solid-phase peptide synthesis; seminalplasmin; 1,6-hexanediol diacrylate-cross-linked polystyrene; polyethylene glycol;

D O I：

10.1016/S0196-9781(00)00207-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel 1,6-hexanediol diacrylate cross-linked resin was prepared that was subsequently functionalized by using chloromethyl methyl ether to afford a high-capacity resin. The resin exhibited good swelling and its application in the successful synthesis of a 13-residue peptide corresponding to the fragment of seminalplasmin has been illustrated. The resin was chemically inert at peptide synthetic conditions. (C) 2000 Elsevier Science Inc. All rights reserved.

引用

页码：773 / 777

页数：5

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