Smart thermo-triggered squirting capsules for nanoparticle delivery

被引：111

作者：

Liu, Li ^{[1
]}

Wang, Wei ^{[1
]}

Ju, Xiao-Jie ^{[1
]}

Xie, Rui ^{[1
]}

Chu, Liang-Yin ^{[1
]}

机构：

[1] Sichuan Univ, Sch Chem Engn, Chengdu 610064, Sichuan, Peoples R China

来源：

SOFT MATTER | 2010年 / 6卷 / 16期

基金：

中国国家自然科学基金;

关键词：

N-ISOPROPYLACRYLAMIDE; PHASE-TRANSITION; COPOLYMER GELS; DRUG-DELIVERY; RELEASE; SYSTEMS;

D O I：

10.1039/c002231d

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A squirting capsule is designed to deliver nanoparticles inspired by the squirting cucumber ejecting its seeds. The capsule has a thermo-sensitive hydrogel shell, and encapsulates nanoparticles by emulsifying the nanoparticle aqueous suspension in the water-in-oil emulsion core. The squirting capsule can completely squirt out the encapsulated nanoparticles with a high momentum, just like a nanoparticle bomb, by the dramatic shrinkage and sudden rupture of the capsule membrane upon heating.

引用

页码：3759 / 3763

页数：5