An unexpected simple synthesis of N-substituted 2-acetoxy-5-arylpyrroles and their hydrolysis to 3 and 4-pyrrolin-2-ones

被引：11

作者：

Tsolomiti, G ^{[1
]}

Tsolomitis, A ^{[1
]}

机构：

[1] Natl Tech Univ Athens, Sch Chem Engn, Organ Chem Lab, Athens 15780, Greece

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 51期

关键词：

2-acetoxypyrroles; 3-pyrrolin-2-ones; 3-aroylpropionamides; acetyl chloride;

D O I：

10.1016/j.tetlet.2004.10.136

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The unexpected synthesis of N-substituted 2-acetoxy-5-arylpyrroles, from the reaction of 3-aroyl-propionamides with a large excess of refluxing acetyl chloride, and their alkaline hydrolysis to 3- and 4-pyrrolin-2-ones, is described. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：9353 / 9355

页数：3

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