A novel endoscopic weight loss therapy using gastric aspiration: results after 6 months

被引:39
作者
Forssell, Henrik [1 ]
Noren, Erik [1 ]
机构
[1] Blekinge Cty Hosp, Dept Surg, S-37185 Karlskrona, Sweden
关键词
PATHOPHYSIOLOGY; GASTROSTOMY;
D O I
10.1055/s-0034-1378097
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background and study aims: Obesity is a major public health problem with few effective treatment options. A novel device for treating obesity, the AspireAssist aspiration therapy system, was evaluated. Patients and methods: After 4 weeks taking a very-low-calorie diet, 25 obese men and women (BMI 39.8 +/- 0.9 kg/m(2)) had the AspireAssist gastrostomy tube placed during a gastroscopy. A low-profile valve was installed 14 days later and aspiration of gastric contents was performed approximately 20 minutes after meals three times per day. Cognitive behavioral therapy was also started. Results: At month 6, mean weight lost was 16.5 +/- 7.8 kg in the 22 subjects who completed 26 weeks of therapy (P=0.001). The mean percentage excess weight lost was 40.8 +/- 19.8% (P=0.001). Two subjects were hospitalized for complications: one subject for pain after gastrostomy tube placement, which was treated with analgesics, and another because of an aseptic intra-abdominal fluid collection 1 day after gastrostomy tube placement. No clinically significant changes in serum potassium or other electrolytes occurred. Conclusion: In this study, substantial weight loss was achieved with few complications using the AspireAssist system, suggesting its potential as an attractive therapeutic device for obese patients.
引用
收藏
页码:68 / 71
页数:4
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