Incomplete Lineage Sorting: Consistent Phylogeny Estimation from Multiple Loci

被引：98

作者：

Mossel, Elchanan ^{[1
]}

Roch, Sebastien ^{[2
,3
]}

机构：

[1] Univ Calif Berkeley, Dept Stat, Berkeley, CA 94720 USA

[2] Univ Calif Los Angeles, Dept Math, Los Angeles, CA 90095 USA

[3] Univ Calif Los Angeles, Bioinformat Program, Los Angeles, CA 90095 USA

来源：

IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS | 2010年 / 7卷 / 01期

基金：

美国国家科学基金会;

关键词：

Incomplete lineage sorting; coalescent process; topological concordance; statistical consistency; SPECIES TREES; GENE TREES; STATISTICAL PHYLOGEOGRAPHY; PROBABILITY; POPULATIONS;

D O I：

10.1109/TCBB.2008.66

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We introduce a simple computationally efficient algorithm for reconstructing phylogenies from multiple gene trees in the presence of incomplete lineage sorting, that is, when the topology of the gene trees may differ from that of the species tree. We show that our technique is statistically consistent under standard stochastic assumptions, that is, it returns the correct tree given sufficiently many unlinked loci. We also show that it can tolerate moderate estimation errors.

引用

页码：166 / 171

页数：6

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