Molecular and cellular insights into the pathogenesis of coronary artery ectasia

被引：26
作者：
Ozturk, Selcuk [1 ]
Yetkin, Ertan [2 ]
Waltenberger, Johannes [3 ,4 ]
机构：
[1] Ankara Educ & Res Hosp, Dept Cardiol, TR-06230 Ankara, Turkey
[2] Private Yenisehir Hosp, Dept Cardiol, Mersin, Turkey
[3] Univ Munster, Fac Med, Munster, Germany
[4] Univ Munster, Cells In Mot Cluster Excellence EXC CiM 1003, Munster, Germany
来源：
CARDIOVASCULAR PATHOLOGY | 2018年 / 35卷
关键词：
Coronary artery ectasia; Atherosclerosis; Pathogenesis; Molecular biology; C-REACTIVE PROTEIN; PLASMA HOMOCYSTEINE LEVELS; ABDOMINAL AORTIC-ANEURYSM; ENDOTHELIAL GROWTH-FACTOR; CONVERTING-ENZYME GENE; INTIMA-MEDIA THICKNESS; NITRIC-OXIDE; INCREASED PREVALENCE; MATRIX METALLOPROTEINASES; MYOCARDIAL-ISCHEMIA;
D O I：
10.1016/j.carpath.2018.04.005
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Coronary artery ectasia describes a local or diffuse dilatation of the epicardial coronary arteries. This review summarizes the molecular and cellular mechanisms involved in the pathogenesis of coronary artery ectasia. Better identification of the pathophysiologic steps will shed light into the clinical significance and may have direct implications for the management strategies of this disease. Additionally, understanding the underlying etiology may help to improve treatment modalities specific to coronary artery ectasia. (C) 2018 Elscvier Inc. All rights reserved.
引用
收藏
页码：37 / 47
页数：11
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