Levobupivacaine A Review of its Use in Regional Anaesthesia and Pain Management

被引:34
作者
Sanford, Mark [1 ]
Keating, Gillian M. [1 ]
机构
[1] Adis, Auckland 0754, New Zealand
关键词
Levobupivacaine; regional anaesthesia; labour analgesia; postoperative pain management; pharmacodynamics; pharmacokinetics; therapeutic use; tolerability; RANDOMIZED CONTROLLED-TRIAL; INGUINAL-HERNIA REPAIR; INTRATHECAL LABOR ANALGESIA; EMERGENCY CESAREAN-SECTION; BRACHIAL-PLEXUS BLOCK; DAY-CASE ARTHROSCOPY; SCIATIC-NERVE BLOCK; LOWER-LIMB SURGERY; EPIDURAL ANALGESIA; RACEMIC BUPIVACAINE;
D O I
10.2165/11203250-000000000-00000
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Levobupivacaine (Chirocaine (R)) is a long-acting amide local anaesthetic that is effective when administered as an epidural, spinal, peripheral nerve or ocular block, or by topical application or local infiltration. In comparative trials, its clinical effects were not generally significantly different from those of bupivacaine or ropivacaine, although there was some variability in efficacy findings in different clinical populations. Levobupivacaine was generally well tolerated. Levobupivacaine provides effective anaesthesia and analgesia for a wide range of clinical populations and is a useful alternative to bupivacaine.
引用
收藏
页码:761 / 791
页数:31
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