Molecular epidemiology of gastric cancer

被引：16
作者：
Starzynska, Teresa [1 ]
机构：
[1] Pomeranian Med Univ, Dept Gastroenterol, PL-71252 Szczecin, Poland
来源：
DIGESTIVE DISEASES | 2007年 / 25卷 / 03期
关键词：
gastric cancer; molecular epidemiology; markers of exposure; markers of susceptibility;
D O I：
10.1159/000103889
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Molecular epidemiology refers to the incorporation of molecular techniques in epidemiological studies. There are different biomarkers in cancer research used for molecular epidemiology including markers of exposure, markers of dose, susceptibility, treatment response, prognosis, altered structure/ function and cancer type. Selected markers, especially those of exposure and susceptibility, are described in an example of gastric cancer. Clinical significance of molecular epidemiology is discussed. Copyright (c) 2007 S. Karger AG, Basel
引用
收藏
页码：222 / 224
页数：3
相关论文
共 13 条
[1]   Molecular epidemiology of cancer [J].
Chen, YC ;
Hunter, DJ .
CA-A CANCER JOURNAL FOR CLINICIANS, 2005, 55 (01) :45-54
[2]   Association of a distinctive strain of Epstein-Barr virus with gastric cancer [J].
Corvalan, A ;
Ding, S ;
Koriyama, C ;
Carrascal, E ;
Carrasquilla, G ;
Backhouse, C ;
Urzua, L ;
Argandoña, J ;
Palma, M ;
Eizuru, Y ;
Akiba, S .
INTERNATIONAL JOURNAL OF CANCER, 2006, 118 (07) :1736-1742
[3]   The role of interleukin-1 polymorphisms in the pathogenesis of gastric cancer (vol 404, pg 398, 2000) [J].
El-Omar, EM ;
Carrington, M ;
Chow, WH ;
McColl, KEL ;
Bream, JH ;
Young, HA ;
Herrera, J ;
Lissowska, J ;
Yuan, CC ;
Rothman, N ;
Lanyon, G ;
Martin, M ;
Fraumeni, JF ;
Rabkin, CS .
NATURE, 2001, 412 (6842) :99-+
[4]   Interleukin-1 polymorphisms associated with increased risk of gastric cancer [J].
El-Omar, EM ;
Carrington, M ;
Chow, WH ;
McColl, KEL ;
Bream, JH ;
Young, HA ;
Herrera, J ;
Lissowska, J ;
Yuan, CC ;
Rothman, N ;
Lanyon, G ;
Martin, M ;
Fraumeni, JF ;
Rabkin, CS .
NATURE, 2000, 404 (6776) :398-402
[5]   Gastric cancer originating from bone marrow-derived cells [J].
Houghton, J ;
Stoicov, C ;
Nomura, S ;
Rogers, AB ;
Carlson, J ;
Li, HC ;
Cai, X ;
Fox, JG ;
Goldenring, JR ;
Wang, TC .
SCIENCE, 2004, 306 (5701) :1568-1571
[6]   A high frequency of BRCA2 gene mutations in Polish families with ovarian and stomach cancer [J].
Jakubowska, A ;
Scott, R ;
Menkiszak, J ;
Gronwald, J ;
Byrski, T ;
Huzarski, T ;
Górski, B ;
Cybulski, C ;
Debniak, T ;
Kowalska, B ;
Starzynska, T ;
Lawniczak, M ;
Narod, S ;
Lubinski, J .
EUROPEAN JOURNAL OF HUMAN GENETICS, 2003, 11 (12) :955-958
[7]  
Ojima H, 2006, ANTICANCER RES, V26, P933
[8]   Global cancer statistics, 2002 [J].
Parkin, DM ;
Bray, F ;
Ferlay, J ;
Pisani, P .
CA-A CANCER JOURNAL FOR CLINICIANS, 2005, 55 (02) :74-108
[9]   Oncogenic T-antigen of JC virus is present frequently in human gastric cancers [J].
Shin, Sung Kwan ;
Li, Mei-Shu ;
Fuerst, Florentine ;
Hotchkiss, Erin ;
Meyer, Richard ;
Kim, Tae I. I. ;
Goel, Ajay ;
Boland, C. Richard .
CANCER, 2006, 107 (03) :481-488
[10]   Molecular epidemiology, pathogenesis and prevention of gastric cancer [J].
Stadtländer, CTKH ;
Waterbor, JW .
CARCINOGENESIS, 1999, 20 (12) :2195-2207
12