Reaction of hydrazonoyl halides 52: Synthesis and antimicrobial activity of some new pyrazolines and 1,3,4-thiadiazolines

被引:20
|
作者
Abdelhamid, Abdou O. [1 ]
Sayed, Abdelwahed R.
机构
[1] Cairo Univ, Fac Sci, Dept Chem, Giza 12622, Egypt
[2] Beni Suef Univ, Fac Sci, Dept Chem, Bani Suwayf, Egypt
关键词
2,3-dihydro-1,3,4-thiadiazoles; arylazothiazoles; hydrazonoyl halides; pyrazolines;
D O I
10.1080/10426500701313938
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
[5-Substituted 2-(3-phenyl-5-substituted 2-pyrazolinyl)(1,3-thiazol-4-yl)] phenyldiazene and 2,3-dihydro-1,3,4-thiadiazoles were synthesized via reactions of hydrazonoyl halides with 5-substituted-3-phenyl-4,5-dihydropyrazole-1-carboximidothionic acid and {[2-2-{aza-2-((methylthioxomethyl)-amino]-vinyl} phenyl)1-azavinyl] amino} methylthiomethane-1-thione, respectively. All structures of the newly synthesized compounds were elucidated by elemental analysis, spectral data, X-ray single crystal, and alternative synthesis methods whenever possible. Some of the new compounds were tested towards bacteria. In general, all tested compounds were capable of a high inhibiting the growth of gram positive and gram negative.
引用
收藏
页码:1767 / 1777
页数:11
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