Ultrathin MXene-Micropattern-Based Field-Effect Transistor for Probing Neural Activity

被引:527
作者
Xu, Bingzhe [1 ]
Zhu, Minshen [2 ]
Zhang, Wencong [1 ]
Zhen, Xu [1 ]
Pei, Zengxia [2 ]
Xue, Qi [2 ]
Zhi, Chunyi [2 ]
Shi, Peng [1 ,3 ]
机构
[1] City Univ Hong Kong, Dept Mech & Biomed Engn, 83 Tat Chee Ave, Kowloon 999077, Hong Kong, Peoples R China
[2] City Univ Hong Kong, Dept Phys & Mat Sci, 83 Tat Chee Ave, Kowloon 999077, Hong Kong, Peoples R China
[3] City Univ Hong Kong, Shenzhen Res Inst, Shenzhen 518057, Peoples R China
基金
中国国家自然科学基金;
关键词
SELECTIVE DETECTION; ELECTROCHEMICAL SENSOR; ASCORBIC-ACID; TI3C2; MXENE; GRAPHENE; DOPAMINE; LI; ANODE; HEMOGLOBIN; BIOSENSOR;
D O I
10.1002/adma.201504657
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A field-effect transistor (FET) based on ultrathin Ti3C2-MXene micropatterns is developed and utilized as a highly sensitive biosensor. The device is produced with the microcontact printing technique, making use of its unique advantages for easy fabrication. Using the MXene-FET device, label-free probing of small molecules in typical biological environments and fast detection of action potentials in primary neurons is demonstrated.
引用
收藏
页码:3333 / 3339
页数:7
相关论文
共 44 条
[1]   Graphene-based hybrid materials and devices for biosensing [J].
Artiles, Mayra S. ;
Rout, Chandra Sekhar ;
Fisher, Timothy S. .
ADVANCED DRUG DELIVERY REVIEWS, 2011, 63 (14-15) :1352-1360
[2]   A Strong Integrated Strength and Toughness Artificial Nacre Based on Dopamine Cross-Linked Graphene Oxide [J].
Cui, Wei ;
Li, Mingzhu ;
Liu, Jiyang ;
Wang, Ben ;
Zhang, Chuck ;
Jiang, Lei ;
Cheng, Qunfeng .
ACS NANO, 2014, 8 (09) :9511-9517
[3]   Nanowire nanosensors for highly sensitive and selective detection of biological and chemical species [J].
Cui, Y ;
Wei, QQ ;
Park, HK ;
Lieber, CM .
SCIENCE, 2001, 293 (5533) :1289-1292
[4]   Graphene Solution-Gated Field-Effect Transistor Array for Sensing Applications [J].
Dankerl, Markus ;
Hauf, Moritz V. ;
Lippert, Andreas ;
Hess, Lucas H. ;
Birner, Stefan ;
Sharp, Ian D. ;
Mahmood, Ather ;
Mallet, Pierre ;
Veuillen, Jean-Yves ;
Stutzmann, Martin ;
Garrido, Jose A. .
ADVANCED FUNCTIONAL MATERIALS, 2010, 20 (18) :3117-3124
[5]   Electrical Detection of DNA Hybridization with Single-Base Specificity Using Transistors Based on CVD-Grown Graphene Sheets [J].
Dong, Xiaochen ;
Shi, Yumeng ;
Huang, Wei ;
Chen, Peng ;
Li, Lain-Jong .
ADVANCED MATERIALS, 2010, 22 (14) :1649-+
[6]   Ti3C2 MXene as a High Capacity Electrode Material for Metal (Li, Na, K, Ca) Ion Batteries [J].
Er, Dequan ;
Li, Junwen ;
Naguib, Michael ;
Gogotsi, Yury ;
Shenoy, Vivek B. .
ACS APPLIED MATERIALS & INTERFACES, 2014, 6 (14) :11173-11179
[7]   Ballistic carbon nanotube field-effect transistors [J].
Javey, A ;
Guo, J ;
Wang, Q ;
Lundstrom, M ;
Dai, HJ .
NATURE, 2003, 424 (6949) :654-657
[8]   Culturing hippocampal neurons [J].
Kaech, Stefanie ;
Banker, Gary .
NATURE PROTOCOLS, 2006, 1 (05) :2406-2415
[9]   Selective Detection of Target Proteins by Peptide-Enabled Graphene Biosensor [J].
Khatayevich, Dmitriy ;
Page, Tamon ;
Gresswell, Carolyn ;
Hayamizu, Yuhei ;
Grady, William ;
Sarikaya, Mehmet .
SMALL, 2014, 10 (08) :1505-1513
[10]   Low-level laser irradiation facilitates fibronectin and collagen type I turnover during tooth movement in rats [J].
Kim, Yong-Deok ;
Kim, Seong-Sik ;
Kim, Seok-Jun ;
Kwon, Dae-Woo ;
Jeon, Eun-Suk ;
Son, Woo-Sung .
LASERS IN MEDICAL SCIENCE, 2010, 25 (01) :25-31